Automated complete blood counter, urine analyzer and urine dipstick test results are correlated with thoma cell counting chamber counts in the diagnosis of dialysis related peritonitis in children.

Autor: Keskin Gözmen Ş; Pediatric Nephrology, University of Health Sciencies, Dr. Behçet Uz Children's Hospital; Department of Pediatric Nephrology, Ismet Kaptan Mh. Sezer Dogan Sk. No: 11, 35210 Izmir, Turkey. Electronic address: sukrankeskingozmen@gmail.com., Serdaroğlu E; Pediatric Nephrology, University of Health Sciencies, Dr. Behçet Uz Children's Hospital; Department of Pediatric Nephrology, Ismet Kaptan Mh. Sezer Dogan Sk. No: 11, 35210 Izmir, Turkey., Dinçel N; Pediatric Nephrology, University of Health Sciencies, Dr. Behçet Uz Children's Hospital; Department of Pediatric Nephrology, Ismet Kaptan Mh. Sezer Dogan Sk. No: 11, 35210 Izmir, Turkey., Erturgut P; Pediatric Nephrology, University of Health Sciencies, Antalya Training and Research Hospital, Department of Pediatric Nephrology, Izmir, Turkey., Başaran C; Pediatric Nephrology, University of Health Sciencies, Tepecik Training and Research Hospital, Department of Pediatric Nephrology, Izmir, Turkey., Devrim F; Pediatric Nephrology, University of Health Sciencies, Dr. Behçet Uz Children's Hospital; Department of Pediatric Nephrology, Ismet Kaptan Mh. Sezer Dogan Sk. No: 11, 35210 Izmir, Turkey., Pehlivan Zorlu B; Pediatric Nephrology, University of Health Sciencies, Dr. Behçet Uz Children's Hospital; Department of Pediatric Nephrology, Ismet Kaptan Mh. Sezer Dogan Sk. No: 11, 35210 Izmir, Turkey., Dur Ö; Pediatric Nephrology, University of Health Sciencies, Dr. Behçet Uz Children's Hospital; Department of Pediatric Nephrology, Ismet Kaptan Mh. Sezer Dogan Sk. No: 11, 35210 Izmir, Turkey., Deniz Kara O; Pediatric Nephrology, University of Health Sciencies, Dr. Behçet Uz Children's Hospital; Department of Pediatric Nephrology, Ismet Kaptan Mh. Sezer Dogan Sk. No: 11, 35210 Izmir, Turkey., Bekiroğlu Yilmaz E; Pediatric Nephrology, University of Health Sciencies, Dr. Behçet Uz Children's Hospital; Department of Pediatric Nephrology, Ismet Kaptan Mh. Sezer Dogan Sk. No: 11, 35210 Izmir, Turkey.
Jazyk: angličtina
Zdroj: Nephrologie & therapeutique [Nephrol Ther] 2022 Dec; Vol. 18 (7), pp. 611-615. Date of Electronic Publication: 2022 Nov 23.
DOI: 10.1016/j.nephro.2022.10.001
Abstrakt: Introduction: Peritoneal dialysis is the treatment of choice for end-stage renal disease. Peritoneal dialysis related peritonitis is of great importance for patient and technical survival. The aim of our study was to evaluate the accuracy and the correlation between the three methods (complete blood count, urinalysis device, urine dipstick test) and with the reference manual method (Thoma Cell Counter Chamber).
Materials and Methods: We retrospectively analyzed 167 peritoneal fluid samples taken from 25 patients receiving peritoneal dialysis treatment. Leukocyte counts were evaluated with Thoma Cell Counter Chamber, complete blood count, urinalysis device and urine dipstick test.
Results: There was a significant positive correlation between Thoma Cell Counter Chamber and complete blood count results (Spearman's rho=0.70), between Thoma Cell Counter Chamber and urinalysis device (Spearman's rho=0.73), and between Thoma Cell Counter Chamber and urine dipstick test (Spearman's rho=0.71). Area under curve for complete blood count, urinalysis device and urine dipstick test were 0.93, 0.94 and 0.89 respectively, indicating good accuracy. Sensitivity and specificity were 89.7% and 86.7% in the complete blood count analysis (associated criterion: 130 cells/mm 3 ). Sensitivity and specificity were 89.7% and 86.7% in the urinalysis device (associated criterion: 10 cells/HPF). Sensitivity and specificity were 79.6% and 91.4% when in the urine dipstick test analysis (associated criterion: +1 positivity). The Bland-Altman plot showed good agreement.
Conclusion: Automatic complete blood count and urinalysis devices have good correlation and agreement with manual method in the diagnosis of peritonitis in the pediatric age group. Urine dipstick test in the home setting can be useful for screening patients with suspected peritonitis.
(Copyright © 2022 Société francophone de néphrologie, dialyse et transplantation. Published by Elsevier Masson SAS. All rights reserved.)
Databáze: MEDLINE
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