The association between victimization and inflammation: A meta-analysis.
Autor: | Chen XY; Department of Applied Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong., Chan KL; Department of Applied Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong. Electronic address: koling.chan@polyu.edu.hk., Lo CKM; Department of Applied Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong., Ho FK; Institute of Health and Wellbeing, University of Glasgow, 1 Lilybank Gardens, Glasgow G12 8RZ, United Kingdom., Leung WC; Department of Obstetrics & Gynaecology, Kwong Wah Hospital, Kowloon, Hong Kong., Ip P; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Pokfulam, Hong Kong. |
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Jazyk: | angličtina |
Zdroj: | Journal of affective disorders [J Affect Disord] 2023 Feb 15; Vol. 323, pp. 108-122. Date of Electronic Publication: 2022 Nov 24. |
DOI: | 10.1016/j.jad.2022.11.063 |
Abstrakt: | Background: To meta-analyze the existing studies examining the association of childhood and adulthood victimization with inflammation and to explore the moderating variables that affect these relationships. Methods: Relevant work published before 28th February 2021 was identified by searching five major databases. We analyzed the cross-sectional data extracted from cross-sectional and longitudinal studies using the random-effects model to estimate the correlation (r) as the pooled effect size and further conducted subgroup analyses and sensitivity analyses. Results: A total of 37 articles finally met the inclusion criteria, including studies for C-reactive protein (CRP) (k = 23; N Limitations: Only a small number of studies on adult victimization were included. In addition, we only analyzed the cross-sectional relationship and did not have sufficient data to compare different types of victimization and single vs. multiple victimizations. Conclusions: Victimization is associated with a heightened inflammatory response. As victimization against children may have a stronger effect than victimization against adults, prevention of victimization targeting the childhood period may be necessary. Studies with more robust methodologies (i.e., representative, longitudinal, and multi-country designs) are needed to confirm these findings and to unpack the underlying mechanisms. Competing Interests: Conflict of Interest The authors declare that they have no competing interests. (Copyright © 2022 Elsevier B.V. All rights reserved.) |
Databáze: | MEDLINE |
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