Nano Zinc Oxide Improves Performance, IGF-I mRNA Expression, Meat Quality, and Humeral Immune Response and Alleviates Oxidative Stress and NF-κB Immunohistochemistry of Broiler Chickens.

Autor: Alian HA; Faculty of Veterinary Medicine, Department of Nutrition and Clinical Nutrition, Suez Canal University, Ismailia, 41522, Egypt. heba.alian@vet.suez.edu.eg., Samy HM; Faculty of Veterinary Medicine, Department of Nutrition and Clinical Nutrition, Suez Canal University, Ismailia, 41522, Egypt., Ibrahim MT; Faculty of Veterinary Medicine, Department of Nutrition and Clinical Nutrition, Suez Canal University, Ismailia, 41522, Egypt., Yusuf MS; Faculty of Veterinary Medicine, Department of Nutrition and Clinical Nutrition, Suez Canal University, Ismailia, 41522, Egypt., Mahmoud MMA; Faculty of Veterinary Medicine, Department of Nutrition and Clinical Nutrition, Suez Canal University, Ismailia, 41522, Egypt.
Jazyk: angličtina
Zdroj: Biological trace element research [Biol Trace Elem Res] 2023 Aug; Vol. 201 (8), pp. 4062-4078. Date of Electronic Publication: 2022 Nov 26.
DOI: 10.1007/s12011-022-03494-y
Abstrakt: A 35-day trial was set to explore the effects of different dietary zinc sources on growth, insulin-like growth factor I (IGF-I) mRNA expression, meat quality, immune response, antioxidant activity, and immunohistochemistry of nuclear factor kappa B (NF-κ7B) of broiler chickens. Ross 308 broiler chicks (n = 156) were randomly assigned into four experimental groups. The G1 received the basal control diet without zinc supplementation; the G2, G3, and G4 were supplemented with zinc oxide, zinc lysine, and nano zinc oxide, respectively, at a level of 40 mg Zn/kg diet. The data revealed that nano zinc oxide linearly improved the overall growth performance parameters. Nano zinc oxide linearly elevated (P < 0.001) mRNA expression of IGF-I followed by G3. The pH value of breast muscle in G4 shows a linearly decreasing value (P < 0.001). Also, the linearly highest expressible release volume percentage and lightness (L*) value with the lowest redness (a*) value (P < 0.05) were recorded in G4 and G3. A numerical increase in the total antibody titer was recorded on the 35 th day in the G3 and G4. A numerical elevation in the superoxide dismutase (SOD) and a numerical reduction in the serum malondialdehyde (MDA) were recorded in the G4. The section of the liver from G4 revealed significantly very low expression of NF-κB staining. It is concluded that nano zinc oxide is considered the more trending zinc source. It had no negative effects on the health status and can be used in broiler diet premix.
(© 2022. The Author(s).)
Databáze: MEDLINE
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