Impact of the COVID-19 Pandemic on Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema in Japan.

Autor: Komori R; J-CREST (Japan Clinical REtina STudy Group), Kagoshima 890-8544, Japan.; Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Yoshida 910-1193, Japan., Takamura Y; J-CREST (Japan Clinical REtina STudy Group), Kagoshima 890-8544, Japan.; Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Yoshida 910-1193, Japan., Yamada Y; Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Yoshida 910-1193, Japan., Morioka M; Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Yoshida 910-1193, Japan., Matsubara H; J-CREST (Japan Clinical REtina STudy Group), Kagoshima 890-8544, Japan.; Department of Ophthalmology, Mie University Graduate School of Medicine, Tsu 514-8507, Japan., Hirano T; J-CREST (Japan Clinical REtina STudy Group), Kagoshima 890-8544, Japan.; Department of Ophthalmology, Shinshu University School of Medicine, Matsumoto 390-8621, Japan., Mitamura Y; J-CREST (Japan Clinical REtina STudy Group), Kagoshima 890-8544, Japan.; Department of Ophthalmology, Tokushima University Graduate School, Tokushima 770-8503, Japan., Shimizu M; J-CREST (Japan Clinical REtina STudy Group), Kagoshima 890-8544, Japan.; Department of Ophthalmology, Sapporo City General Hospital, Sapporo 060-8604, Japan., Kusuhara S; J-CREST (Japan Clinical REtina STudy Group), Kagoshima 890-8544, Japan.; Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan., Murakami T; J-CREST (Japan Clinical REtina STudy Group), Kagoshima 890-8544, Japan.; Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8576, Japan., Nihei R; J-CREST (Japan Clinical REtina STudy Group), Kagoshima 890-8544, Japan.; Department of Ophthalmology, National Defense Medical College, Tokorozawa 359-8513, Japan., Ueda T; J-CREST (Japan Clinical REtina STudy Group), Kagoshima 890-8544, Japan.; Department of Ophthalmology, Nara Medical University, Kashihara 634-8522, Japan., Kunikata H; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan., Jujo T; J-CREST (Japan Clinical REtina STudy Group), Kagoshima 890-8544, Japan.; Department of Ophthalmology, St Marianna University School of Medicine, Kawasaki 216-8511, Japan., Terasaki H; J-CREST (Japan Clinical REtina STudy Group), Kagoshima 890-8544, Japan.; Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Japan., Nagasato D; J-CREST (Japan Clinical REtina STudy Group), Kagoshima 890-8544, Japan.; Department of Ophthalmology, Saneikai Tsukazaki Hospital, Himeji 671-1227, Japan., Noda K; Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan., Osaka R; Department of Ophthalmology, Kagawa University Hospital, Kita 761-0793, Japan., Nagai K; J-CREST (Japan Clinical REtina STudy Group), Kagoshima 890-8544, Japan.; Department of Ophthalmology, Gunma University Hospital, Maebashi 371-8511, Japan., Yoshida S; J-CREST (Japan Clinical REtina STudy Group), Kagoshima 890-8544, Japan.; Department of Ophthalmology, Faculty of Medicine, Kurume University, Kurume 830-0011, Japan., Nozaki M; Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan., Noma H; Department of Ophthalmology, Tokyo Medical University Hachioji Medical Center, Tokyo 193-0998, Japan., Ishigooka G; J-CREST (Japan Clinical REtina STudy Group), Kagoshima 890-8544, Japan.; Department of Ophthalmology, Osaka Medical and Pharmaceutical University, Takatsuki 569-8686, Japan., Takahashi A; Department of Ophthalmology, Faculty of Medicine, Kyorin University, Mitaka 181-8611, Japan., Sawada O; J-CREST (Japan Clinical REtina STudy Group), Kagoshima 890-8544, Japan.; Department of Ophthalmology, Shiga University of Medical Science, Otsu 520-2192, Japan., Kimura K; J-CREST (Japan Clinical REtina STudy Group), Kagoshima 890-8544, Japan.; Department of Ophthalmology, Yamaguchi University School of Medicine, Ube 755-0046, Japan., Inatani M; Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Yoshida 910-1193, Japan.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2022 Nov 16; Vol. 11 (22). Date of Electronic Publication: 2022 Nov 16.
DOI: 10.3390/jcm11226794
Abstrakt: Anti-vascular endothelial growth factor (VEGF) therapy for diabetic macular edema (DME) improves visual acuity. However, repeated injections during routine outpatient visits are required to maintain this effect. The recent sudden global outbreak of coronavirus disease 2019 (COVID-19) had a major impact on daily life, including medical care, such as the provision of VEGF therapy. We retrospectively investigated the relationship between the number of anti-VEGF injections for DME and the number of new COVID-19-positive patients at 23 centers in Japan. We also surveyed ophthalmologists regarding the impact of the COVID-19 pandemic on anti-VEGF therapy. In the third and fourth waves of the pandemic, when the number of infected patients increased, the number of injections significantly decreased. In the first, third, and fourth waves, the number of injections increased significantly during the last month of each wave. Approximately 60.9% of ophthalmologists reported that the number of injections decreased after the pandemic. Of the facilities, 52.2% extended the clinic visit intervals; however, there was no significant difference in the actual number of injections given between before and after the pandemic. Although the number of injections temporarily decreased, Japanese ophthalmologists maintained the total annual number of anti-VEGF injections for DME during the pandemic.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje