| Autor: |
de Carvalho Cardoso R; Healthy Sciences School, Brazilian Institute of Medicine and Rehabilitation (IBMR), Rio de Janeiro 22631-002, Brazil., Rezende B; Department of Pharmacology and Psychobiology, Roberto Alcântara Gomes Institute Biology (IBRAG), Rio de Janeiro State University (UERJ), Rio de Janeiro 20551-030, Brazil., Alencar AKN; Department of Biomedical Engineering, Tulane University, New Orleans, LA 70118, USA., Fontes-Dantas FL; Department of Pharmacology and Psychobiology, Roberto Alcântara Gomes Institute Biology (IBRAG), Rio de Janeiro State University (UERJ), Rio de Janeiro 20551-030, Brazil., Montes GC; Department of Pharmacology and Psychobiology, Roberto Alcântara Gomes Institute Biology (IBRAG), Rio de Janeiro State University (UERJ), Rio de Janeiro 20551-030, Brazil. |
| Jazyk: |
angličtina |
| Zdroj: |
Tropical medicine and infectious disease [Trop Med Infect Dis] 2022 Nov 21; Vol. 7 (11). Date of Electronic Publication: 2022 Nov 21. |
| DOI: |
10.3390/tropicalmed7110390 |
| Abstrakt: |
The number of publications on the development of arthritic pain after CHIKV infection is increasing; however, there is still a gap in the pathophysiological mechanisms that explain these outcomes. In this review, we conducted a descriptive analysis of the findings of patients to understand their prognosis and to explore therapeutic options. Here, we searched the Cochrane, BVS, PubMed, and Scielo databases using the keywords "arthritis", "pain", "arbovirus", "disease", "arthritogenic", and "arthralgia" during the 2000 to 2022 period. Descriptive analyses were conducted to understand the association between CHIKV infection and arthritogenic pain. The present study shows the persistence of acute phase signals for months, making the chronic phase still marked by the presence of arthralgia, often disabling under stimuli, such as temperature variation. CHIKV infection appears to be remarkably similar to rheumatoid arthritis, since both diseases share common symptoms. Once diagnosed, patients are mostly treated with analgesics, nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and disease modifying anti-rheumatic drugs (DMARD). As there are no prophylactic measures or specific treatments for arboviruses, this study gathered information on the development and manifestations of arthritogenic pain. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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