Use of Autologous Platelet Rich Plasma (A-PRP) for Postpartum Perineal Repair Failure: A Case Report.

Autor: Akhoundova F; Department of Pediatrics, Gynecology and Obstetrics, Geneva University Hospitals, 1205 Geneva, Switzerland., Schumacher F; Department of Pediatrics, Gynecology and Obstetrics, Geneva University Hospitals, 1205 Geneva, Switzerland., Léger M; Department of Pediatrics, Gynecology and Obstetrics, Geneva University Hospitals, 1205 Geneva, Switzerland., Berndt S; Department of Plastic, Reconstructive and Aesthetic Surgery, Faculty of Medicine, Geneva University Hospitals, 1205 Geneva, Switzerland.; Regen Lab SA, 1052 Le Mont-sur-Lausanne, Switzerland., Martinez de Tejada B; Department of Pediatrics, Gynecology and Obstetrics, Geneva University Hospitals, 1205 Geneva, Switzerland., Abdulcadir J; Department of Pediatrics, Gynecology and Obstetrics, Geneva University Hospitals, 1205 Geneva, Switzerland.
Jazyk: angličtina
Zdroj: Journal of personalized medicine [J Pers Med] 2022 Nov 17; Vol. 12 (11). Date of Electronic Publication: 2022 Nov 17.
DOI: 10.3390/jpm12111917
Abstrakt: Perineal wound dehiscence is an uncommon but important postpartum complication. In many cases, it leads to extreme pain and urinary and defecation problems. For up to several weeks, it can interfere with the mother's daily activity, affecting psychosexual health and body image. The best way to manage perineal wound breakdown (resuturing vs. spontaneous closure) after childbirth remains controversial. A-PRP is the autologous human plasma containing an increased platelet concentration, rich in growth factors, and mediators with hemostatic, anti-inflammatory, and antimicrobial properties. It accelerates the natural healing process. Even though A-PRP is widely used in orthopedics and dermatology, its use in gynecological injuries is limited. We describe here a case of a woman with postpartum perineal dehiscence treated with A-PRP with positive outcomes.
Databáze: MEDLINE