Family Herpesviridae and neuroinfections: current status and research in progress.
| Autor: | Carneiro VCS; Fundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Virologia Molecular, Rio de Janeiro, RJ, Brasil., Pereira JG; Fundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Virologia Molecular, Rio de Janeiro, RJ, Brasil., de Paula VS; Fundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Virologia Molecular, Rio de Janeiro, RJ, Brasil. |
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| Jazyk: | angličtina |
| Zdroj: | Memorias do Instituto Oswaldo Cruz [Mem Inst Oswaldo Cruz] 2022 Nov 21; Vol. 117, pp. e220200. Date of Electronic Publication: 2022 Nov 21 (Print Publication: 2022). |
| DOI: | 10.1590/0074-02760220200 |
| Abstrakt: | This article addresses the relationship between human herpesviruses (HHVs) and neuroinfections. Alphaherpesviruses, betaherpesviruses and gammaherpesviruses are neurotropic viruses that establish latency and exhibit reactivation capacity. Encephalitis and meningitis are common in cases of HHV. The condition promoted by HHV infection is a purported trigger for certain neurodegenerative diseases. Ongoing studies have identified an association between HSV-1 and the occurrence of Alzheimer's disease, multiple sclerosis and infections by HHV-6 and Epstein-Barr virus. In this review, we highlight the importance of research investigating the role of herpesviruses in the pathogenesis of diseases that affect the nervous system and describe other studies in progress. |
| Databáze: | MEDLINE |
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