Complications Post-COVID-19 and Risk Factors among Patients after Six Months of a SARS-CoV-2 Infection: A Population-Based Prospective Cohort Study.

Autor: Domènech-Montoliu S; Emergency Service Hospital de la Plana, 12540 Villarreal, Castellon, Spain., Puig-Barberà J; Vaccines Research Area FISABIO, 46020 Valencia, Spain., Pac-Sa MR; Public Health Center, 12003 Castelló de la Plana, Castellon, Spain., Vidal-Utrillas P; Health Centers I and II, 12530 Borriana, Castellon, Spain., Latorre-Poveda M; Emergency Service Hospital de la Plana, 12540 Villarreal, Castellon, Spain., Del Rio-González A; Health Centers I and II, 12530 Borriana, Castellon, Spain., Ferrando-Rubert S; Health Centers I and II, 12530 Borriana, Castellon, Spain., Ferrer-Abad G; Health Centers I and II, 12530 Borriana, Castellon, Spain., Sánchez-Urbano M; Emergency Service Hospital de la Plana, 12540 Villarreal, Castellon, Spain., Aparisi-Esteve L; Carinyena Health Center, 12540 Villarreal, Castellon, Spain., Badenes-Marques G; Emergency Service Hospital de la Plana, 12540 Villarreal, Castellon, Spain., Cervera-Ferrer B; Emergency Service Hospital de la Plana, 12540 Villarreal, Castellon, Spain., Clerig-Arnau U; Emergency Service Hospital de la Plana, 12540 Villarreal, Castellon, Spain., Dols-Bernad C; Health Center, 12200 Onda, Castellon, Spain., Fontal-Carcel M; Health Center, 12600 La Vall d'Uixó, Castellon, Spain., Gomez-Lanas L; Emergency Service Hospital de la Plana, 12540 Villarreal, Castellon, Spain., Jovani-Sales D; Emergency Service Hospital de la Plana, 12540 Villarreal, Castellon, Spain., León-Domingo MC; Villa Fátima School, 12530 Borriana, Castellon, Spain., Llopico-Vilanova MD; Emergency Service Hospital de la Plana, 12540 Villarreal, Castellon, Spain., Moros-Blasco M; Health Centers I and II, 12530 Borriana, Castellon, Spain., Notari-Rodríguez C; Emergency Service Hospital de la Plana, 12540 Villarreal, Castellon, Spain., Ruíz-Puig R; Emergency Service Hospital de la Plana, 12540 Villarreal, Castellon, Spain., Valls-López S; Emergency Service Hospital de la Plana, 12540 Villarreal, Castellon, Spain., Arnedo-Pena A; Public Health Center, 12003 Castelló de la Plana, Castellon, Spain.; Department of Health Science, Public University Navarra, 31006 Pamplona, Navarra, Spain.; Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.
Jazyk: angličtina
Zdroj: Epidemiologia (Basel, Switzerland) [Epidemiologia (Basel)] 2022 Feb 10; Vol. 3 (1), pp. 49-67. Date of Electronic Publication: 2022 Feb 10.
DOI: 10.3390/epidemiologia3010006
Abstrakt: In October 2020, we conducted a population-based prospective cohort study to determine post-COVID-19 complications, recovery, return to usual health, and associated risk factors in 536 cases of COVID-19 outbreak in Borriana (Spain) by administering an epidemiological questionnaire via phone interviews. A total of 484 patients participated (90.3%), age mean 37.2 ± 17.1 years, and 301 females (62.2%). Mild illness was the most common COVID-19 manifestation. After six months, 160 patients (33.1%) suffered at least one complication post-COVID-19, and 47 (29.4%) of them sought medical assistance. The most frequent persistent symptoms were hair loss, fatigue, loss of smell or taste, and headache. Risk factors associated with a complication were female sex (adjusted relative risk, [aRR] = 1.93 95% confidence interval [CI] 1.41-2.65), age 35 years and above (aRR = 1.50 95% CI 1.14-1.99), B blood group (aRR = 1.51 95% CI 1.04-2.16), current smoker (RR = 1.61 95% CI 1.02-2.54), and at least a COVID-19 exposure (aRR = 2.13 95% CI 1.11-4.09). Male sex, age younger than 35 years, and low COVID-19 exposures were associated with better recovery and return to usual health. A third of patients presented persistent symptoms compatible with the long-COVID-19 syndrome. In conclusion, an active medical follow-up of post-COVID-19 patients must be implemented.
Databáze: MEDLINE