Cell cycle: Making waves to coordinate the entry into mitosis.

Autor: Wilmott ZM; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Raff JW; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK. Electronic address: jordan.raff@path.ox.ac.uk.
Jazyk: angličtina
Zdroj: Current biology : CB [Curr Biol] 2022 Nov 21; Vol. 32 (22), pp. R1262-R1264.
DOI: 10.1016/j.cub.2022.10.030
Abstrakt: How do very large cells coordinate their entry into mitosis? A new study shows that the bistability of the Cdk/Cyclin system allows cells to generate either 'trigger waves' or 'sweep waves' that drive cells into mitosis in different ways with distinct consequences.
Competing Interests: Declaration of interests The authors declare no competing interests.
(Copyright © 2022 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE