Brucella canis discospondylitis in 33 dogs.

Autor: Long C; Wheat Ridge Animal Hospital, Wheat Ridge, CO, United States., Burgers E; Diagnostic Imaging, P.C, Denver, CO, United States., Copple C; Diagnostic Imaging, P.C, Denver, CO, United States., Stainback L; Veterinary Neurology Center, Phoenix, AZ, United States., Packer RA; College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, United States., Kopf K; VCA Alameda East Veterinary Hospital, Denver, CO, United States., Schmidt J; Wheat Ridge Animal Hospital, Wheat Ridge, CO, United States., Emch S; VCA Alameda East Veterinary Hospital, Denver, CO, United States., Windsor R; Wheat Ridge Animal Hospital, Wheat Ridge, CO, United States.
Jazyk: angličtina
Zdroj: Frontiers in veterinary science [Front Vet Sci] 2022 Nov 04; Vol. 9, pp. 1043610. Date of Electronic Publication: 2022 Nov 04 (Print Publication: 2022).
DOI: 10.3389/fvets.2022.1043610
Abstrakt: Objective: To describe the clinical and imaging findings of 33 dogs with Brucella canis discospondylitis (BDS).
Animals: 33 client owned dogs from four veterinary specialty hospitals within Colorado and Arizona with at least one positive B. canis test and spinal diagnostic imaging.
Procedures: Retrospective review of signalment, physical and neurological examination findings, laboratory results, B. canis serology, and diagnostic imaging of 33 dogs with BDS. All imaging was reviewed by a board-certified veterinary neurologist. Radiographs were reviewed by a board-certified veterinary radiologist blinded to MRI and CT findings.
Results: 31/33 (94%) dogs were <5 years old (median = 2.5 years, mean = 2.9 years, range 0.5-10 years). 21/29 (72%) dogs had signs of nonspecific pain, spinal pain, or lameness for >3 months (median = 6 months, mean = 8.2 months, range 5 days-4 years). Fever was seen in only 4/28 (14%) dogs. Multifocal lesions were evident on radiographs in 21/29 (72%) dogs and MRI in 12/18 (67%) dogs. Smooth, round, central end-plate lysis, defined as "hole punch" lesions, were identified radiographically in 25/29 (86%) dogs. Vertebral physitis or spondylitis without discitis was evident on MRI in 7/18 (39%) dogs.
Clinical Relevance: Dogs with BDS typically present at a young age with a long duration of clinical signs. Identification of radiographic "hole punch" lesions and MRI evidence of vertebral physitis, spondylitis, and paravertebral inflammation without discitis should increase suspicion for BDS. BDS may be increasing in frequency in the southwestern United States, and dogs with signs of chronic spinal pain and/or lameness should be screened for B. canis .
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2022 Long, Burgers, Copple, Stainback, Packer, Kopf, Schmidt, Emch and Windsor.)
Databáze: MEDLINE