IgA vasculitis with nephritis (Henoch-Schönlein purpura) after COVID-19: A case series and review of the literature.

Autor:	Oñate I; Departamento de Nefrología, Hospital Universitario Severo Ochoa, Madrid, Spain. Electronic address: ireneonate@outlook.com., Ortiz M; Departamento de Nefrología, Hospital Universitario Severo Ochoa, Madrid, Spain., Suso A; Departamento de Nefrología, Hospital Universitario Severo Ochoa, Madrid, Spain., Mon C; Departamento de Nefrología, Hospital Universitario Severo Ochoa, Madrid, Spain., Galindo K; Departamento de Nefrología, Hospital Universitario Severo Ochoa, Madrid, Spain., Lentisco C; Departamento de Nefrología, Hospital Universitario Severo Ochoa, Madrid, Spain., Camacho R; Departamento de Nefrología, Hospital Universitario Severo Ochoa, Madrid, Spain., Sánchez M; Departamento de Nefrología, Hospital Universitario Severo Ochoa, Madrid, Spain., Oliet A; Departamento de Nefrología, Hospital Universitario Severo Ochoa, Madrid, Spain., Ortega O; Departamento de Nefrología, Hospital Universitario Severo Ochoa, Madrid, Spain., Herrero JC; Departamento de Nefrología, Hospital Universitario Severo Ochoa, Madrid, Spain., Cortés JA; Departamento de Anatomía Patológica, División de Patología Renal, Hospital Clínico San Carlos, Madrid, Spain., Pascual A; Departamento de Anatomía Patológica, División de Patología Renal, Hospital Clínico San Carlos, Madrid, Spain.
Jazyk:	angličtina
Zdroj:	Nefrologia [Nefrologia (Engl Ed)] 2022 Jul-Aug; Vol. 42 (4), pp. 481-489. Date of Electronic Publication: 2022 Nov 15.
DOI:	10.1016/j.nefroe.2022.11.003
Abstrakt:	COVID-19 most related glomerular disease to date seems to be collapsing glomerulopathy, mostly in young Afroamerican patients with APOL1 gene risk alleles. However, in our population, predominant in elderly Caucasian patients, most biopsied pathology since the beginning of the pandemic has been IgA nephritis or Schönlein-Henoch purpura. Since the description of the first case of this entity after SARS-CoV-2 infection by our research group, three more cases have arisen, which are described in the following article. In contrast to the rest of IgA vasculitis cases reported, our patients presented more renal function deterioration and all of them required immunosupresive therapy. Moreover, some showed incomplete recovery of renal function. This case series strengthens the hypothesis that SARS-CoV-2 infection may be another trigger of this pathology. (Copyright © 2021 Sociedad Española de Nefrología. Published by Elsevier España, S.L.U. All rights reserved.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu