Graft Arterial Dissection and Thrombosis After Kidney Transplantation With Undiagnosed Fibromuscular Dysplasia From a Deceased Donor: Case Report and Review.

Autor: Meltzer AZ; Department of Surgery, Transplantation, and Gastroenterology at Semmelweis University, Faculty of Medicine, Budapest, Hungary. Electronic address: meltzer.anna_zsofia@med.semmelweis-univ.hu., Fintha A; 1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Faculty of Medicine, Budapest, Hungary., Cseprekál O; Department of Surgery, Transplantation, and Gastroenterology at Semmelweis University, Faculty of Medicine, Budapest, Hungary., Somogyi D; Medical Imaging Centre, Department of Radiology, Semmelweis University, Faculty of Medicine, Budapest, Hungary., Szabó J; Department of Surgery, Transplantation, and Gastroenterology at Semmelweis University, Faculty of Medicine, Budapest, Hungary., Kóbori L; Department of Surgery, Transplantation, and Gastroenterology at Semmelweis University, Faculty of Medicine, Budapest, Hungary., Rózsa B; Department of Surgery, Transplantation, and Gastroenterology at Semmelweis University, Faculty of Medicine, Budapest, Hungary., Piros L; Department of Surgery, Transplantation, and Gastroenterology at Semmelweis University, Faculty of Medicine, Budapest, Hungary., Huszty G; Department of Surgery, Transplantation, and Gastroenterology at Semmelweis University, Faculty of Medicine, Budapest, Hungary.
Jazyk: angličtina
Zdroj: Transplantation proceedings [Transplant Proc] 2022 Nov; Vol. 54 (9), pp. 2603-2607. Date of Electronic Publication: 2022 Nov 16.
DOI: 10.1016/j.transproceed.2022.10.049
Abstrakt: Background: Fibromuscular dysplasia (FMD), a relatively frequent arterial deformity with an estimated prevalence of 2% to 6% has been sporadically reported during deceased donor kidney donations. Only 8 case reports are available in the previous literature.
Case Presentation: In our work, implantation of 2 kidneys from the same deceased donor with macroscopically evident and later histologically confirmed FMD are presented, one of which ended up as acute arterial complication. Renal arteries were cut short to allow safe implantation, but arterial dissection and thrombosis led to graft loss in the early perioperative period in the latter case.
Conclusions: Although resection of the arterial segments affected by FMD as a routine may allow implantation, macroscopically healthy-looking arteries might still be affected and thus carry elevated postoperative risk. The aim of our case report is to make proposal for an onsite diagnosis of FMD in case of clinical suspicion.
(Copyright © 2022. Published by Elsevier Inc.)
Databáze: MEDLINE
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