A Case Report of Anti-phospholipid Syndrome With Lower Extremity Arterial Thrombosis That Didn't Respond to Heparin and Direct Oral Anticoagulation: Ultimately, the Patient Agreed to Oral Warfarin.
| Autor: | Abdulrahman ZA; Internal Medicine, Mather Hospital/Northwell Health, Port Jefferson, USA., Azeez H; Internal Medicine, Mather Hospital/Zucker School of Medicine/Northwell Health, Port Jefferson, USA., Hassan R; Internal Medicine, United Health Services Program, New York, USA., Ng J; Pulmonary and Critical Care Medicine, Northwell Health, Port Jefferson, USA., Kaell A; Internal Medicine/Rheumatology, Northwell Health, Port Jefferson, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2022 Nov 08; Vol. 14 (11), pp. e31230. Date of Electronic Publication: 2022 Nov 08 (Print Publication: 2022). |
| DOI: | 10.7759/cureus.31230 |
| Abstrakt: | In the absence of known thrombophilia or factors associated with thrombotic tendency, clinicians are more likely to think of antiphospholipid syndrome in patients presenting with venous thrombosis than in those with arterial thrombosis. We present a case of acute lower extremity arterial ischemia in a female smoker. Despite multiple surgical interventions and treatment with several different anticoagulants, our patient developed bilateral lower extremity thrombi. Ultimately, after developing a pulmonary embolism, she accepted to be on warfarin. She switched to warfarin without recurrence of her arterial thrombosis. We describe the challenging management of her critical limb ischemia and review the pertinent literature on the controversy surrounding optimal anticoagulation in such patients. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Abdulrahman et al.) |
| Databáze: | MEDLINE |
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