Long term WEB results - still going strong at 5 years?

Autor:	Alpay K; Department of Radiology, Turku University Hospital, Turku, Finland., Nania A; Department of Clinical Neurosciences, University of Edinburgh, Edinburgh, UK., Raj R; Department of Neurosurgery, Helsinki University Hospital and University of Helsinki, Finland., Numminen J; Department of Radiology, Helsinki University Hospital, Helsinki, Finland., Parkkola R; Department of Radiology, Turku University Hospital, Turku, Finland., Rautio R; Department of Radiology, Turku University Hospital, Turku, Finland., Downer J; Department of Clinical Neurosciences, University of Edinburgh, Edinburgh, UK.
Jazyk:	angličtina
Zdroj:	Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences [Interv Neuroradiol] 2024 Aug; Vol. 30 (4), pp. 517-523. Date of Electronic Publication: 2022 Nov 17.
DOI:	10.1177/15910199221139542
Abstrakt:	Objective: The aim of our multi-center study is to examine 5-year radiological outcomes of intracranial aneurysms (IAs) treated with the Woven EndoBridge (WEB). Methods: All patients treated with WEB between January 2013 and December 2016 were included. Patient and aneurysm characteristic data was collected from the electronic patient record. Aneurysm occlusion was assessed using a 3-grade scale: complete occlusion, neck remnant, and aneurysm remnant. Complete occlusion and neck remnant were considered as adequate occlusion, whereas aneurysm remnant was assessed as an inadequate occlusion. Results: A total of 66 patients (72.7% female) with 66 IAs (n = 25 acutely ruptured) were treated with WEB. The mean age of patients was 55.6 years (range: 36-71 years). The mean width of the aneurysm neck was 4.5 mm (range: 2-9 mm). 5-year imaging follow-up data was not available for 16.6% patients (n = 11). During the follow up period, 14.5% of IAs (n = 8/55) required retreatment within 24 months of initial treatment with the WEB. A total of 55 IAs were analyzed for 5-year radiological outcome. Of these, including IAs required retreatment, 47.3% of IAs (n = 26/55) were occluded completely, 36.4% (n = 20/55) had neck remnant and 16.3% (n = 9/55) had recanalized. 83.7% of IAs were occluded adequately. None of the IAs rebled after initial treatment with WEB. Conclusion: WEB can provide acceptable adequate occlusion rates at 5 years. Furthermore, recanalization appears to be unlikely after the first two years post-treatment. The results of large studies are needed to confirm these promising long term radiological outcomes. Competing Interests: Declaration of conflicting interestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: KA has received personal research grants from Radiological Society of Finland and Maire Taponen Foundation. RR is consultant for Microvention, Stryker and Medtronic. JD is proctor and consultant for Microvention, Stryker and Neurologic/Acandis. Other authors report no conflict of interest.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu