Risk of atrial fibrillation and stroke among older men exposed to prolonged endurance sport practice: a 10-year follow-up. The Birkebeiner Ageing Study and the Tromsø Study.

Autor:	Johansen KR; School of Sport Sciences, UiT The Arctic University of Norway, Tromso, Norway kristoffer.r.johansen@uit.no.; Centre for Research and Education, University Hospital of North Norway, Tromso, Norway., Ranhoff AH; Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Internal Medicine, Diakonhjemmet Hospital, Oslo, Norway., Sørensen E; Department of Internal Medicine, Diakonhjemmet Hospital, Oslo, Norway.; Department of Medical Research, Bærum Hospital, Vestre Viken Hospital Trust, N-1346 Gjettum, Norway., Nes BM; Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway., Heitmann KA; School of Sport Sciences, UiT The Arctic University of Norway, Tromso, Norway., Apelland T; Department of Medical Research, Bærum Hospital, Vestre Viken Hospital Trust, N-1346 Gjettum, Norway., Bucher Sandbakk S; Department for Teacher Education, Norwegian University of Science and Technology, Trondheim, Norway., Wilsgaard T; Department of Community Medicine, UiT The Arctic University of Norway, Tromso, Norway., Løchen ML; Department of Community Medicine, UiT The Arctic University of Norway, Tromso, Norway.; Department of Cardiology, University Hospital of North Norway, Tromso, Norway., Thelle DS; Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.; School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg Sahlgrenska Academy, Goteborg, Sweden., Morseth B; School of Sport Sciences, UiT The Arctic University of Norway, Tromso, Norway.; Centre for Research and Education, University Hospital of North Norway, Tromso, Norway., Myrstad M; Department of Medical Research, Bærum Hospital, Vestre Viken Hospital Trust, N-1346 Gjettum, Norway.; Department of Internal Medicine, Bærum Hospital, Vestre Viken Hospital Trust, N-1346 Gjettum, Norway.
Jazyk:	angličtina
Zdroj:	Open heart [Open Heart] 2022 Nov; Vol. 9 (2).
DOI:	10.1136/openhrt-2022-002154
Abstrakt:	Aims: Endurance sport practice is associated with a high prevalence of atrial fibrillation (AF), which increases the risk of stroke in the general population. However, stroke risk in endurance athletes with AF is sparsely investigated. Most studies have been limited by design and are largely restricted to younger and middle-aged populations. Thus, we aimed to investigate AF and stroke risk in older athletes exposed to prolonged endurance training. Method: During a 10-year period, 505 male athletes aged ≥65 years frequently participating in a long-distance ski race were compared with 1867 men of the same age from the general population. The main exposure was endurance sport practice with self-reported AF and stroke as outcomes. Stroke risk was further examined by joint modelling of AF and endurance practice. Statistical analysis was conducted with a modified Poisson model. Results: Athletes (median age: 68, range: 65-90) participated in a long-distance ski race over a median of 14 years (range: 1-53). Prevalence (28.5% vs 17.8%) and adjusted risk of AF (risk ratio (RR): 1.88, 95% CI: 1.49 to 2.37) were higher in athletes compared with non-athletes, whereas the prevalence (5.4% vs 9.7%) and risk of stroke were lower (RR: 0.60, 95% CI: 0.37 to 0.95). Compared with athletes without AF, risk of stroke was twofold in athletes (RR: 2.38, 95% CI: 1.08 to 5.24) and nearly fourfold in non-athletes (RR: 3.87, 95% CI: 1.98 to 7.57) with AF. Conclusion: Although older male endurance athletes experienced an increased risk of AF, the long-term risk of stroke was substantially reduced compared with non-athletes. Competing Interests: Competing interests: M-LL has received lecture fees from Bayer, Sanofi and BMS/Pfizer not related to this study. MM has received lecture fees from Bayer, Boehringer-Ingelheim, Bristol Myers Squibb, mSD and Pfizer not related to this work. (© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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