Length of Hospital Stay and Its Predictors Among Neonatal Sepsis Patients: A Retrospective Follow-Up Study.

Autor:	Sisay EA; Department of Pharmacology and Clinical Pharmacy, Addis Ababa University, Addis Ababa, Ethiopia., Mengistu BL; Department of Pharmacology and Clinical Pharmacy, Addis Ababa University, Addis Ababa, Ethiopia., Taye WA; Department of Pediatrics and Child Health, Addis Ababa University, Addis Ababa, Ethiopia., Fentie AM; Department of Pharmacology and Clinical Pharmacy, Addis Ababa University, Addis Ababa, Ethiopia., Yabeyu AB; Department of Pharmacy, Ambo University, Ambo, Ethiopia.
Jazyk:	angličtina
Zdroj:	International journal of general medicine [Int J Gen Med] 2022 Nov 09; Vol. 15, pp. 8133-8142. Date of Electronic Publication: 2022 Nov 09 (Print Publication: 2022).
DOI:	10.2147/IJGM.S385829
Abstrakt:	Introduction: Sepsis is common among neonates, and is often fatal. Hospitalization results in severe nosocomial infections which could be resistant to antibiotics. It also incurs higher fees for medical care. Methods: A retrospective follow-up study, which includes 206 neonates, was conducted to assess the length of hospital stay among neonatal sepsis patients from September 2018 to September 2020 at TASH Hospital, Addis Ababa, Ethiopia. Data were collected from medical charts. Mean length of hospital stay was compared using independent sample t -tests. Risk factors for length of stay were identified using binary logistic regression analysis. Results: All neonates stayed a total of 325 days, which gives 75,512 neonate-days. Neonates who stayed more than 7 days had low mean birth weight and higher mean age at admission. Mean length of stay was higher among neonates with comorbid illness, neonates with drug therapy problems and male neonates. Even though the mean length of stay is shorter among neonates with maternal PROM and CS delivery, these maternal factors were found to be insignificant in the multivariate logistic regression. Discussion: Similar to other studies, neonates with low birth weight and comorbidity had a longer hospital stay. Neonates with maternal PROM and CS delivery had a shorter stay. But these maternal factors, identified by prior studies as risk factors for neonatal sepsis and its mortality, are not found to be predictors of prolonged hospitalization. Having neurologic features and drug therapy problems among neonates with sepsis prolonged hospital stay. Conclusion: The mean length of stay varies with respect to maternal and neonatal factors. Lower birth weight, presence of neurologic features, presence of comorbidity, presence of drug therapy problems and being male are found to be predictors of a longer hospital stay among neonates with sepsis. Competing Interests: The authors report no conflicts of interest in this work. (© 2022 Sisay et al.)
Databáze:	MEDLINE
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