Low-grade fibromyxoid sarcoma in labial mucosa: Report of a rare case in a pediatric patient.

Autor: Penafort PVM; Department of Oral Diagnosis, Semiology and Pathology Areas, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil., de Pauli Paglioni M; Department of Oral Diagnosis, Semiology and Pathology Areas, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil., Siqueira SAC; Department of Pathology, University of São Paulo Medical School, São Paulo, Brazil., Falzoni R; Department of Pathology, University of São Paulo Medical School, São Paulo, Brazil., de Mendonça RMH; Department of Dentistry, Boldrini Hospital, Campinas, São Paulo, Brazil., Lopes MA; Department of Oral Diagnosis, Semiology and Pathology Areas, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil., Vargas PA; Department of Oral Diagnosis, Semiology and Pathology Areas, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil., Santos-Silva AR; Department of Oral Diagnosis, Semiology and Pathology Areas, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil. Electronic address: alan@unicamp.br.
Jazyk: angličtina
Zdroj: Oral oncology [Oral Oncol] 2022 Dec; Vol. 135, pp. 106243. Date of Electronic Publication: 2022 Nov 13.
DOI: 10.1016/j.oraloncology.2022.106243
Abstrakt: Low-grade fibromyxoid sarcoma (LGFMS) is a malignant neoplasm of soft tissue, which occurs mainly in extremities. In this study, we described a rare case of LGFMS arising in the labial mucosa, in a 7-year-old male patient, who presented a painless multilobulated growth with an evolution time of 12 months. An incisional biopsy was performed and microscopic examination revealed a proliferation of bland regular spindle cells in an alternating myxoid and hyalinized stroma. The tumor cells showed a strong cytoplasmic immunoreactivity for MUC4 and low cell proliferation index measured by Ki-67 antibody. The diagnosis of LGFMS was established and the patient was referred for surgical treatment at a pediatric oncology hospital.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2022 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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