Artificial iris implantation in congenital aniridia: A systematic review.

Autor: Romano D; Ophthalmology Clinic, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, Ophthalmology Clinic, University of Brescia, Brescia, Italy., Bremond-Gignac D; Ophthalmology Department, Hôpital Universitaire Necker-Enfants Malades, APHP, Paris, France; INSERM, UMRS1138, Team 17, Université Sorbonne Paris Cité, Centre de Recherche des Cordeliers, Paris, France., Barbany M; Institut de Microcirurgia Ocular, Barcelona, Spain., Rahman A; School of Medicine, University of Liverpool, Liverpool L69 3GE, UK., Mauring L; Eye Clinic and Genetics and Personalized Medicine Clinic, Tartu University Hospital, Tartu, Estonia., Semeraro F; Ophthalmology Clinic, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, Ophthalmology Clinic, University of Brescia, Brescia, Italy., Cursiefen C; Department of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany., Lagali N; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden., Romano V; Ophthalmology Clinic, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, Ophthalmology Clinic, University of Brescia, Brescia, Italy. Electronic address: vito.romano@gmail.com.
Jazyk: angličtina
Zdroj: Survey of ophthalmology [Surv Ophthalmol] 2023 Jul-Aug; Vol. 68 (4), pp. 794-808. Date of Electronic Publication: 2022 Nov 12.
DOI: 10.1016/j.survophthal.2022.11.001
Abstrakt: Congenital aniridia is a rare, panocular disorder with a main phenotypic characteristic of a partial or complete absence of the iris existing alongside other ocular morbidities such as cataract, keratopathy, optic nerve and foveal hypoplasia, and nystagmus. The iris abnormality, however, often leads to symptoms such as photophobia, glare, and decreased visual acuity, as well as cosmetic dissatisfaction. Current management options for the iris deficit include colored iris contact lenses, corneal tattooing, and tinted contact lenses. Symptoms arising from small iris defects can be resolved with surgical management using micro-tying suture techniques such as McCannel or Siepser. Currently, larger iris defects can be treated with artificial iris implants. New prosthetic options range from colored intraocular lenses to flexible custom-made silicone iris implants. With a range of therapeutic options available and given the challenges of multiple comorbidities in aniridia, we evaluate the literature relating to the use of artificial iris implants in congenital aniridia, with a focus on the different surgical implantation techniques, the clinical outcomes achieved, complications occurred, and risk of bias of the studies included.
(Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: