Effectiveness of fluoride-containing toothpastes associated with different technologies to remineralize enamel after pH cycling: an in vitro study.

Autor: Fernandes NLS; Stricto Sensu Post-Graduate Program in Dentistry, Department of Clinical and Community Dentistry, Health Science Center, Federal University of Paraiba (UFPB), João Pessoa, PB, Brazil., Silva JGVC; Postgraduate Program in Dentistry, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., de Sousa EBG; DentalSchool, Federal University of Paraiba, João Pessoa, PB, Brazil., D'Alpino PHP; Triplet Biotechnology Solution, São Paulo, SP, Brazil.; POSMAT - Post-Graduate Program in Materials Science and Technology, School of Sciences, São Paulo State University (UNESP), Bauru, SP, Brazil., de Oliveira AFB; Department of Morphology, Health Science Center, Federal University of Paraiba, João Pessoa, PB, Brazil., de Jong EJ; Research & Development, Inspektor Research Systems BV, Amsterdam, The Netherlands., Sampaio FC; Stricto Sensu Post-Graduate Program in Dentistry, Department of Clinical and Community Dentistry, Health Science Center, Federal University of Paraiba (UFPB), João Pessoa, PB, Brazil. fcsampa@gmail.com.
Jazyk: angličtina
Zdroj: BMC oral health [BMC Oral Health] 2022 Nov 14; Vol. 22 (1), pp. 489. Date of Electronic Publication: 2022 Nov 14.
DOI: 10.1186/s12903-022-02429-2
Abstrakt: Background: To evaluate the efficacy of fluoride-containing toothpastes with different technologies to remineralize artificial caries lesions in enamel.
Methods: Bovine enamel blocks were divided into three thirds: intact (untreated), demineralized (artificial caries lesion), and treated (caries lesion, pH cycling with dentifrices). Enamel blocks were randomly distributed into five groups (n = 12): Fluoride-free toothpaste, Colgate Oral Care (NC); Arginine-containing toothpaste, Colgate Total Daily Repair (PC); Silicate-based fluoride toothpaste: REFIX technology, regenerador + sensitive (RDC), NR-5 technology, Regenerate Enamel Science (RES), and NOVAMIN technology, Sensodyne Repair and Protect (SRP). The specimens were submitted to a pH cycling model for 6 days. The efficacy of the toothpastes was estimated by calculating the surface microhardness recovery (%SMH R ) and the fluorescence recovery (ΔF RE ) with quantitative light-induced fluorescence. The cross-sectional micromorphology of the enamel surface was also assessed using scanning electron microscopy. Elemental analyses (weight%) were determined with an energy-dispersive X-ray spectrometer (EDS). The results were compared to that of the control (NC). Data were statistically analyzed (5%).
Results: %SMH R could be ranked as follows: RDC = PC = RES = SRP > NC. Significantly higher %SMH R and ΔF RE means were observed after enamel treatment with RDC (22.7 and 46.9, respectively). PC (%SMH R  = 18.8) was as efficacious as RDC to recover the surface microhardness with a significantly lower mean of ΔF RE (19.5). Only RDC was able to promote the formation of a mineralized layer on the surface of enamel enriched with silicon on the surface.
Conclusions: The silicate-based fluoride toothpaste containing REFIX technology demonstrated greater efficacy in the remineralizing artificial caries than the other products.
(© 2022. The Author(s).)
Databáze: MEDLINE
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