Efficacy of professionally administered chemical agents as an adjunctive treatment to sub-marginal instrumentation during the therapy of peri-implant mucositis.

Autor: Dommisch H; Department of Periodontology, Oral Medicine and Oral Surgery, Dentistry, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Hoedke D; Department of Periodontology, Oral Medicine and Oral Surgery, Dentistry, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Valles C; Department of Periodontology, Facultad de Odontología, Universitat Internacional de Catalunya, Barcelona, Spain., Vilarrasa J; Department of Periodontology, Facultad de Odontología, Universitat Internacional de Catalunya, Barcelona, Spain., Jepsen S; Department of Periodontology, Operative and Preventive Dentistry, University Hospital Bonn, Bonn, Germany., Pascual La Rocca A; Department of Periodontology, Facultad de Odontología, Universitat Internacional de Catalunya, Barcelona, Spain.
Jazyk: angličtina
Zdroj: Journal of clinical periodontology [J Clin Periodontol] 2023 Jun; Vol. 50 Suppl 26, pp. 146-160. Date of Electronic Publication: 2022 Dec 16.
DOI: 10.1111/jcpe.13747
Abstrakt: Aim: To evaluate the efficacy of professionally administered chemical agents as an adjunctive treatment to sub-marginal instrumentation (SMI) in the therapy of peri-implant mucositis.
Materials and Methods: The primary outcome criteria were reduction in bleeding on probing (BOP), whereas resolution of disease, elimination of suppuration, including suppuration on probing, reduction of peri-implant probing pocket depth, reduction of plaque, and patient-reported outcome measures were considered as secondary outcome parameters. A literature search was performed on three electronic databases (01/1980 to 05/2022) focused on clinical studies with at least 3 months of follow-up, and meta-analyses were performed when appropriate.
Results: From a total of 139 publications, 40 articles were identified for full-text reading, and 5 randomized controlled clinical trials (RCTs) on antimicrobial photodynamic therapy (aPDT), 1 RCT on chlorhexidine (CHX), and 1 RCT on sodium hypochlorite (NaOCl) were included. Three studies had a low risk of bias and four had a mid-level (some concerns) risk of bias. The application of aPDT, 0.95% NaOCl, or 0.12% CHX as an adjunctive treatment to SMI showed no difference in changes in BOP and PD compared with SMI alone (p > .05).
Conclusions: Within the limitations of this review and based on a low level of evidence from seven RCTs, it is concluded that the professional adjunctive topical application of aPDT, 0.95% NaOCl, and 0.12% CHX may not be effective to improve changes for BOP and PD when compared with SMI alone.
(© 2022 The Authors. Journal of Clinical Periodontology published by John Wiley & Sons Ltd.)
Databáze: MEDLINE