Antifouling activity of isonitrosoacetanilides against microfouling and macrofouling.

Autor: Agostini VO; Regenera Moléculas do Mar, Centro de Biotecnologia da Universidade Federal do Rio Grande Do Sul (UFRGS), Av. Bento Gonçalves, 9500, Bairro Agronomia, Porto Alegre, RS, 91501-970, Brazil. nessaochi@gmail.com., Martinez ST; Centro Interdisciplinar em Energia e Ambiente-CIEnAm, Universidade Federal da Bahia, Salvador, BA, 40170-115, Brazil.; Centro Universitário SENAI-CIMATEC, Salvador, BA, 41650-010, Brazil., Muxagata E; Laboratório de Zooplâncton, Instituto de Oceanografia da Universidade Federal do Rio Grande (FURG), Av. Itália, Km 8, Caixa Postal, 474, Rio Grande, RS, 96203-900, Brazil., Macedo AJ; Laboratório de Biofilmes e Diversidade Microbiana, Centro de Biotecnologia da, Universidade Federal do Rio Grande do Sul (UFRGS), Av. Bento Gonçalves, 9500, Bairro Agronomia, Porto Alegre, RS, 91501-900, Brazil., Pinho GLL; Laboratório de Microcontaminantes Orgânicos e Ecotoxicologia Aquática, Instituto de Oceanografia da Universidade Federal do Rio Grande (FURG), Caixa Postal, 474, CEP, Rio Grande, RS, 96203-900, Brazil.
Jazyk: angličtina
Zdroj: Environmental science and pollution research international [Environ Sci Pollut Res Int] 2023 Feb; Vol. 30 (10), pp. 26435-26444. Date of Electronic Publication: 2022 Nov 11.
DOI: 10.1007/s11356-022-24016-2
Abstrakt: Biofouling is responsible for structural and economic damage to man-made surfaces. Antifouling paints with biocides have been applied to structures to avoid organism adhesion; however, they have high toxicity and are not able to prevent all biofouling processes, necessitating the periodic mechanical removal of organisms and paint reapplication. Thus, there is an urgent demand for novel, effective, and environmentally friendly antifouling alternatives. As isonitrosoacetanilide is the precursor for many compounds with antibacterial activity, we believe that it could have antifouling activity against microfouling and, consequently, against macrofouling. The aim of this work was to investigate the antifouling potential of six isonitrosoacetanilide compounds and their toxicity. The compounds were employed at different concentrations (0.625-1.25-2.5-5-10 µg mL -1 ) in this study. The biofilm and planktonic bacteria inhibition and biofilm eradication potential were evaluated by crystal violet assay, while Amphibalus amphitrite barnacle settlement was evaluated by cyprid settlement assay. Toxicity evaluation (LC 50 and EC 50 ) was performed with A. amphitrite nauplii II and cyprid larvae. At least one of the tested concentrations of 4-Br-INA, 4-CH 3 -INA, and 2-Br-INA compounds showed nontoxic antifouling activity against microfouling (antibiofilm) and macrofouling (antisettlement). However, only 4-CH 3 -INA and 2-Br-INA also showed biofilm eradication potential. These compounds with antibiofilm activity and nontoxic effects could be combined with acrylic base paint resin or added directly into commercial paints in place of toxicant biocides to cover artificial structures as friendly antifouling agents.
(© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
Externí odkaz: