| Autor: |
Pogreba-Brown K; Department of Epidemiology and Biostatistics, The University of Arizona, Tucson, Arizona, USA., Boyd K; Department of Epidemiology and Biostatistics, The University of Arizona, Tucson, Arizona, USA., Schaefer K; Department of Epidemiology and Biostatistics, The University of Arizona, Tucson, Arizona, USA., Austhof E; Department of Epidemiology and Biostatistics, The University of Arizona, Tucson, Arizona, USA., Armstrong A; Department of Epidemiology and Biostatistics, The University of Arizona, Tucson, Arizona, USA., Owusu-Dommey A; Department of Epidemiology and Biostatistics, The University of Arizona, Tucson, Arizona, USA., Villa-Zapata L; College of Pharmacy, Mercer University, Atlanta, Georgia, USA., Arora M; Department of Community, Environment and Policy, The University of Arizona, Tucson, Arizona, USA., McClelland JD; Arizona Health Sciences Library, The University of Arizona, Tucson, Arizona, USA., Hoffman S; U.S. Department of Agriculture, Washington, District of Columbia, USA. |
| Abstrakt: |
Listeria monocytogenes is a relatively rare but highly pathogenic bacterium that can cause foodborne infections. In the United States there are ∼1600 cases per year, 94% of which result in hospitalizations and 20% in deaths. Per-case burden is high because the disease also causes serious complications, including sepsis, encephalitis, meningitis, miscarriage, and stillbirth. The disease burden of L. monocytogenes is underestimated because some of these acute complications can also result in long-term outcomes. In this article, we conducted a scoping review of L. monocytogenes complications and longer term outcomes from articles published between 2000 and 2018. Search terms were developed for four major databases (PubMed, Scopus, Web of Science, and Embase) as well as gray literature and hand searches of review articles. We follow standard scoping review methodology and assessment. Out of 10,618 unique articles originally identified, 115 articles were included, representing 49 unique outcomes. The majority of studies were cohort designs ( n = 67) and conducted in the United States or Europe ( n = 98). Four major outcome groupings were death, neurological disorders, sepsis, and congenital infection. This study identifies substantial research on the common acute complications of L. monocytogenes and few long-term consequences of L. monocytogenes . We identify the need for additional studies to determine the longer term impacts of these acute complications. |
