Associations of device-measured physical activity and sedentary time with quality of life and fatigue in newly diagnosed breast cancer patients: Baseline results from the AMBER cohort study.

Autor: Vallance JK; Faculty of Health Disciplines, Athabasca University, Athabasca, Alberta, Canada., Friedenreich CM; Department of Cancer Epidemiology and Prevention Research, Alberta Health Services, Calgary, Alberta, Canada.; Departments of Oncology and Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Wang Q; Department of Cancer Epidemiology and Prevention Research, Alberta Health Services, Calgary, Alberta, Canada., Matthews CE; Division of Cancer Epidemiology and Genetics, US National Cancer Institute, Bethesda, Maryland, USA., Yang L; Department of Cancer Epidemiology and Prevention Research, Alberta Health Services, Calgary, Alberta, Canada.; Departments of Oncology and Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., McNeely ML; Faculty of Rehabilitation Medicine, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada., Culos-Reed SN; Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada., Bell GJ; Faculty of Kinesiology, Sport, and Recreation, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada., Morielli AR; Department of Cancer Epidemiology and Prevention Research, Alberta Health Services, Calgary, Alberta, Canada., McNeil J; Department of Kinesiology, School of Health and Human Sciences, University of North Carolina at Greensboro, Greensboro, North Carolina, USA., Dickau L; Department of Cancer Epidemiology and Prevention Research, Alberta Health Services, Calgary, Alberta, Canada., Cook D; Faculty of Kinesiology, Sport, and Recreation, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada., Courneya KS; Faculty of Kinesiology, Sport, and Recreation, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada.
Jazyk: angličtina
Zdroj: Cancer [Cancer] 2023 Jan 15; Vol. 129 (2), pp. 296-306. Date of Electronic Publication: 2022 Nov 11.
DOI: 10.1002/cncr.34531
Abstrakt: Background: This study examined associations of device-measured physical activity and sedentary time with quality of life (QOL) and fatigue in newly diagnosed breast cancer patients in the Alberta Moving Beyond Breast Cancer (AMBER) cohort study.
Methods: After diagnosis, 1409 participants completed the SF-36 version 2 and the Fatigue Scale, wore an ActiGraph device on their right hip to measure physical activity, and an activPAL device on their thigh to measure sedentary time (sitting/lying) and steps. ActiGraph data was analyzed using a hybrid machine learning method (R Sojourn package, Soj3x) and activPAL data were analyzed using activPAL algorithms (PAL Software version 8). Quantile regression was used to examine cross-sectional associations of QOL and fatigue with steps, physical activity, and sedentary hours at the 25th, 50th, and 75th percentiles of the QOL and fatigue distributions.
Results: Total daily moderate and vigorous physical activity (MVPA) hours was positively associated with better physical QOL at the 25th (β = 2.14, p = <.001), 50th (β = 1.98, p = <.001), and 75th percentiles (β = 1.25, p = .003); better mental QOL at the 25th (β = 1.73, p = .05) and 50th percentiles (β = 1.07, p = .03); and less fatigue at the 25th (β = 4.44, p < .001), 50th (β = 3.08, p = <.001), and 75th percentiles (β = 1.51, p = <.001). Similar patterns of associations were observed for daily steps. Total sedentary hours was associated with worse fatigue at the 25th (β = -0.58, p = .05), 50th (β = -0.39, p = .06), and 75th percentiles (β = -0.24, p = .02). Sedentary hours were not associated with physical or mental QOL.
Conclusions: MVPA and steps were associated with better physical and mental QOL and less fatigue in newly diagnosed breast cancer patients. Higher sedentary time was associated with greater fatigue symptoms.
(© 2022 American Cancer Society.)
Databáze: MEDLINE
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