Chemical Composition of Tagetes patula Flowers Essential Oil and Hepato-Therapeutic Effect against Carbon Tetrachloride-Induced Toxicity (In-Vivo).
Autor: | Aati HY; Department of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11495, Saudi Arabia., Emam M; Phytochemistry and Plant Systematics Department, National Research Centre, Giza 12622, Egypt., Al-Qahtani J; Department of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11495, Saudi Arabia., Aati S; UWA Dental School, University of Western Australia, 17 Monash Avenue, Nedlands, WA 6009, Australia., Aati A; Rokn Al-Madaein Pharmaceutical Warehouse Co., P.O. Box 2990, Riyadh 11495, Saudi Arabia., Wanner J; Kurt Kitzing Co., Hinterm Alten Schloss 21, D-86757 Wallerstein, Germany., Seif MM; Toxicology and Food Contaminants Department, Food Industries and Nutrition Research Institute, National Research Centre, Giza 12622, Egypt. |
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Jazyk: | angličtina |
Zdroj: | Molecules (Basel, Switzerland) [Molecules] 2022 Oct 25; Vol. 27 (21). Date of Electronic Publication: 2022 Oct 25. |
DOI: | 10.3390/molecules27217242 |
Abstrakt: | The liver is a crucial organ among body organs due to its wide functions, in particular, detoxification and metabolism. Exposure to detrimental chemicals or viral infections may provoke liver dysfunction and ultimately induce liver tissue damage. Finding natural substances for liver disease treatment to overcome the conventional treatments' side effects has attracted the attention of researchers worldwide. Our current work was conducted to investigate the hepato-therapeutic activities of essential oil (EO) isolated from Tagetes patula flowers. EO was extracted using the hydro-distillation (HD) technique and its chemical composition was identified by GC/MS. Then, the hepatic treatment potential of extracted EO was evaluated in vivo against CCL Competing Interests: The authors declare no conflict of interest. |
Databáze: | MEDLINE |
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