Integrating Microfluidics and Electronics in Point-of-Care Diagnostics: Current and Future Challenges.

Autor: Annese VF; Center for Nano Science and Technology@PoliMi, Istituto Italiano di Tecnologia, 20133 Milan, Italy.; James Watt School of Engineering, University of Glasgow, Glasgow G12 8QQ, UK., Hu C; James Watt School of Engineering, University of Glasgow, Glasgow G12 8QQ, UK.
Jazyk: angličtina
Zdroj: Micromachines [Micromachines (Basel)] 2022 Nov 07; Vol. 13 (11). Date of Electronic Publication: 2022 Nov 07.
DOI: 10.3390/mi13111923
Abstrakt: Point-of-Care (POC) diagnostics have gained increasing attention in recent years due to its numerous advantages over conventional diagnostic approaches. As proven during the recent COVID-19 pandemic, the rapidity and portability of POC testing improves the efficiency of healthcare services and reduces the burden on healthcare providers. There are hundreds of thousands of different applications for POC diagnostics, however, the ultimate requirement for the test is the same: sample-in and result-out. Many technologies have been implemented, such as microfluidics, semiconductors, and nanostructure, to achieve this end. The development of even more powerful POC systems was also enabled by merging multiple technologies into the same system. One successful example is the integration of microfluidics and electronics in POC diagnostics, which has simplified the sample handling process, reduced sample usage, and reduced the cost of the test. This review will analyze the current development of the POC diagnostic systems with the integration of microfluidics and electronics and discuss the future challenges and perspectives that researchers might have.
Databáze: MEDLINE