The threshold tracking nerve conduction study technique: Experience of clinical users unfamiliar with a research-grade neuronal excitability system.

Autor:	McIlduff CE; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Wainger BJ; Department of Neurology, Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Department of Anesthesiology, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA., Freeman RL; Center for Autonomic and Peripheral Nerve Disorders, Beth Israel Deaconess Medical Center, Boston, MA, USA., Samaan S; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Yator I; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Gutierrez H; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Verga S; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Rutkove SB; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Jazyk:	angličtina
Zdroj:	Clinical neurophysiology practice [Clin Neurophysiol Pract] 2022 Oct 13; Vol. 7, pp. 319-324. Date of Electronic Publication: 2022 Oct 13 (Print Publication: 2022).
DOI:	10.1016/j.cnp.2022.08.003
Abstrakt:	Objective: To 1) explore if clinical electrophysiologists with different degrees of experience performing standard nerve conduction studies could run a threshold tracking nerve conduction study (TTNCS) protocol and 2) learn how clinical users view a research-grade TTNCSs neuronal excitability system. Methods: Five clinical electrophysiologists conducted a TTNCS session using QTracS and then completed a questionnaire describing their impressions. Results: All of the electrophysiologists completed the QTracS protocol on an initial attempt. Perceived strengths comprised the ease of preparatory steps and quick protocol speed. Identified drawbacks included an unwieldly user-interface. The electrophysiologists indicated that knowledge of TTNCS principles and applications would be critical for incorporation of the method into clinical use. Conclusions: This pilot study suggests that clinical electrophysiologists can carry out TTNCSs with a research-grade system. The development of a more user-friendly program, along with dedicated education and training, could lead to wider application of the TTNCS technique. Significance: Considered together with clinical presentation and other biomarkers, increased use of TTNCSs could provide improved assessment of neuromuscular disease and treatment response. Competing Interests: None. (© 2022 International Federation of Clinical Neurophysiology. Published by Elsevier B.V.)
Databáze:	MEDLINE
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