Central hypersomnia and chronic insomnia: expanding the spectrum of sleep disorders in long COVID syndrome - a prospective cohort study.

Autor: Moura AEF; Hospital Universitário Walter Cantídio, Neurology Service, Universidade Federal do Ceará, Fortaleza, Brazil.; Department of Clinical Medicine, Universidade Federal do Ceará, Rua Prof. Costa Mendes, 1608 - 4° andar - Rodolfo Teófilo, Fortaleza, Ceará, Brazil., Oliveira DN; Hospital Universitário Walter Cantídio, Neurology Service, Universidade Federal do Ceará, Fortaleza, Brazil.; Department of Clinical Medicine, Universidade Federal do Ceará, Rua Prof. Costa Mendes, 1608 - 4° andar - Rodolfo Teófilo, Fortaleza, Ceará, Brazil., Torres DM; Hospital Universitário Walter Cantídio, Neurology Service, Universidade Federal do Ceará, Fortaleza, Brazil., Tavares-Júnior JWL; Hospital Universitário Walter Cantídio, Neurology Service, Universidade Federal do Ceará, Fortaleza, Brazil.; Department of Clinical Medicine, Universidade Federal do Ceará, Rua Prof. Costa Mendes, 1608 - 4° andar - Rodolfo Teófilo, Fortaleza, Ceará, Brazil., Nóbrega PR; Hospital Universitário Walter Cantídio, Neurology Service, Universidade Federal do Ceará, Fortaleza, Brazil.; Department of Clinical Medicine, Universidade Federal do Ceará, Rua Prof. Costa Mendes, 1608 - 4° andar - Rodolfo Teófilo, Fortaleza, Ceará, Brazil., Braga-Neto P; Hospital Universitário Walter Cantídio, Neurology Service, Universidade Federal do Ceará, Fortaleza, Brazil. pbraganeto@ufc.br.; Department of Clinical Medicine, Universidade Federal do Ceará, Rua Prof. Costa Mendes, 1608 - 4° andar - Rodolfo Teófilo, Fortaleza, Ceará, Brazil. pbraganeto@ufc.br.; Center of Health Sciences, Universidade Estadual do Ceará, Fortaleza, Brazil. pbraganeto@ufc.br., Sobreira-Neto MA; Hospital Universitário Walter Cantídio, Neurology Service, Universidade Federal do Ceará, Fortaleza, Brazil.; Department of Clinical Medicine, Universidade Federal do Ceará, Rua Prof. Costa Mendes, 1608 - 4° andar - Rodolfo Teófilo, Fortaleza, Ceará, Brazil.
Jazyk: angličtina
Zdroj: BMC neurology [BMC Neurol] 2022 Nov 09; Vol. 22 (1), pp. 417. Date of Electronic Publication: 2022 Nov 09.
DOI: 10.1186/s12883-022-02940-7
Abstrakt: Introduction: Long-onset COVID syndrome has been described in patients with COVID-19 infection with persistence of symptoms or development of sequelae beyond 4 weeks after the onset of acute symptoms, a medium- and long-term consequence of COVID-19. This syndrome can affect up to 32% of affected individuals, with symptoms of fatigue, dyspnea, chest pain, cognitive disorders, insomnia, and psychiatric disorders. The present study aimed to characterize and evaluate the prevalence of sleep symptoms in patients with long COVID syndrome.
Methodology: A total of 207 patients with post-COVID symptoms were evaluated through clinical evaluation with a neurologist and specific exams in the subgroup complaining of excessive sleepiness.
Results: Among 189 patients included in the long COVID sample, 48 (25.3%) had sleep-related symptoms. Insomnia was reported by 42 patients (22.2%), and excessive sleepiness (ES) was reported by 6 patients (3.17%). Four patients with ES were evaluated with polysomnography and test, multiple sleep latencies test, and actigraphic data. Two patients had a diagnosis of central hypersomnia, and one had narcolepsy. A history of steroid use was related to sleep complaints (insomnia and excessive sleepiness), whereas depression was related to excessive sleepiness. We observed a high prevalence of cognitive complaints in these patients.
Conclusion: Complaints related to sleep, such as insomnia and excessive sleepiness, seem to be part of the clinical post-acute syndrome (long COVID syndrome), composing part of its clinical spectrum, relating to some clinical data.
(© 2022. The Author(s).)
Databáze: MEDLINE
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