Appropriateness of antibiotic use in community hospitals in rural Newfoundland and Labrador.

Autor: Wheeler ED; Faculty of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada., McDonald G; Eastern Health Region, St. John's, Newfoundland and Labrador, Canada., Daley P; Faculty of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.; Eastern Health Region, St. John's, Newfoundland and Labrador, Canada.
Jazyk: angličtina
Zdroj: Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada [J Assoc Med Microbiol Infect Dis Can] 2021 Jul 20; Vol. 6 (2), pp. 114-118. Date of Electronic Publication: 2021 Jul 20 (Print Publication: 2021).
DOI: 10.3138/jammi-2020-0041
Abstrakt: Background: Surveillance of the appropriateness of antimicrobial prescribing can identify targets for quality improvement in antimicrobial stewardship. Our objective was to measure antibiotic prescription prevalence, indication, and appropriateness at three rural community hospitals in a 1-day point prevalence study.
Methods: Inpatient antibiotic prescriptions given at three community hospitals on April 24, 2019 were provided by the hospital pharmacies. These prescriptions were analyzed using the Australian National Antimicrobial Prescribing Survey (NAPS) tool. Prescriptions were assessed by an infectious diseases physician and analyzed per prescription.
Results: Eighty prescriptions given to 58 inpatients were included. Antibiotic treatment prevalence was 58/120 beds (48.3%), and overall appropriateness was 37/80 prescriptions (46.3%). The most prescribed antibiotics were ceftriaxone (17 [21.3%]; 47.1% appropriate), piperacillin-tazobactam (10 [12.5%]; 10.0% appropriate), and moxifloxacin (9 [11.3%]; 0% appropriate). The most common indications were respiratory tract infections (36 [45.0%]; 36.1% appropriate), skin and soft tissue infections (14 [17.5%]; 78.6% appropriate), and urinary tract infections (9 [11.3%]; 11.1% appropriate). Of the 80 prescriptions, 50 (62.5%) documented an indication, and 71 (88.8%) documented a stop or review date.
Conclusions: We observed a high treatment prevalence and low appropriateness. Overall appropriateness was lower than in urban hospitals.
Competing Interests: The authors declare that they have no competing interests.
(Copyright © 2021, Association of Medical Microbiology and Infectious Disease Canada (AMMI Canada).)
Databáze: MEDLINE