Ethyl 2-[4-(4-meth-oxy-benz-yl)-3-methyl-6-oxopyridazin-1-yl]acetate.

Autor: Zaoui Y; Laboratory of Medicinal Chemistry, Drug Sciences Research Center, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat, Morocco., Assila H; Laboratory of Medicinal Chemistry, Drug Sciences Research Center, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat, Morocco., Mague JT; Department of Chemistry, Tulane University, New Orleans, LA 70118, USA., Alsubari A; Laboratory of Medicinal Chemistry, Faculty of Clinical Pharmacy, 21 September University, Yemen., Taoufik J; Laboratory of Medicinal Chemistry, Drug Sciences Research Center, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat, Morocco., Ramli Y; Laboratory of Medicinal Chemistry, Drug Sciences Research Center, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat, Morocco., Ansar M; Laboratory of Medicinal Chemistry, Drug Sciences Research Center, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat, Morocco.
Jazyk: angličtina
Zdroj: IUCrData [IUCrdata] 2022 Jun 07; Vol. 7 (Pt 6), pp. x220582. Date of Electronic Publication: 2022 Jun 07 (Print Publication: 2022).
DOI: 10.1107/S241431462200582X
Abstrakt: In the title mol-ecule, C 17 H 20 N 2 O 4 , the inner part of the ester substituent is nearly perpendicular to the di-hydro-pyridazine ring, forming a dihedral angle of 83.21 (7)°. In the crystal, inversion dimers are formed by pairwise C-H⋯O inter-actions with the dimers connected into chains extending along the b -axis direction by C-H⋯π(ring) inter-actions. The chains are connected by π-stacking inter-actions to give corrugated layers parallel to the ab plane. The terminal ethyl group is disordered over two two sets of sites with the major component having a site occupancy factor of 0.715 (10).
(© Zaoui et al. 2022.)
Databáze: MEDLINE
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