One-stage hybrid coronary revascularization for the treatment of multivessel coronary artery disease- Periprocedural and long-term results from the "HYBRID-COR" feasibility study.

Autor:	Sanetra K; Clinic of Cardiovascular Surgery, Andrzej Frycz Modrzewski Krakow University, Kraków, Poland.; Department of Cardiac Surgery, American Heart of Poland, Bielsko-Biała, Poland., Buszman PP; Department of Cardiology, Andrzej Frycz Modrzewski Krakow University, Kraków, Poland.; Department of Cardiology, American Heart of Poland, Bielsko-Biała, Poland.; Center for Cardiovascular Research and Development, American Heart of Poland, Katowice, Poland., Jankowska-Sanetra J; Department of Cardiology, American Heart of Poland, Bielsko-Biała, Poland., Cisowski M; Department of Cardiac Surgery, University Hospital, Institute of Medical Sciences, University of Opole, Opole, Poland., Fil W; Department of Cardiology, Andrzej Frycz Modrzewski Krakow University, Kraków, Poland.; Department of Cardiology, American Heart of Poland, Bielsko-Biała, Poland., Gorycki B; Department of Cardiology, American Heart of Poland, Bielsko-Biała, Poland., Bochenek A; Department of Cardiac Surgery, American Heart of Poland, Bielsko-Biała, Poland.; Center for Cardiovascular Research and Development, American Heart of Poland, Katowice, Poland.; Faculty of Medicine, University of Technology, Katowice, Poland., Slabon-Turska M; Department of Obstetrics and Gynecology, Provincial Specialist Hospital, Wrocław, Poland., Konopko M; Department of Cardiology, Andrzej Frycz Modrzewski Krakow University, Kraków, Poland., Kaźmierczak P; American Heart of Poland, Katowice, Poland., Gerber W; Department of Cardiac Surgery, American Heart of Poland, Bielsko-Biała, Poland.; Faculty of Medicine, University of Technology, Katowice, Poland., Milewski K; Department of Cardiology, American Heart of Poland, Bielsko-Biała, Poland.; Center for Cardiovascular Research and Development, American Heart of Poland, Katowice, Poland.; Faculty of Medicine, University of Technology, Katowice, Poland., Buszman PE; Department of Epidemiology, Medical University of Silesia, Katowice, Poland.
Jazyk:	angličtina
Zdroj:	Frontiers in cardiovascular medicine [Front Cardiovasc Med] 2022 Oct 19; Vol. 9, pp. 1016255. Date of Electronic Publication: 2022 Oct 19 (Print Publication: 2022).
DOI:	10.3389/fcvm.2022.1016255
Abstrakt:	Background: The constant growth of interest in hybrid coronary artery revascularization (HCR) is apparent. Yet, few studies report outcomes of the one-stage HCR. Consequently, the status of such procedures is not adequately supported in clinical guidelines. The aim of this study was to report the safety, feasibility, and long term-outcomes of the one-stage HCR. Methods and Results: Patients were enrolled in the prospective one-stage hybrid coronary revascularization program (HYBRID-COR). They underwent a one-stage hybrid revascularization procedure while on double antiplatelet therapy (DAPT) with Ticagrelor: endoscopic atraumatic coronary artery bypass grafting (EACAB) for revascularization of the left anterior descending (LAD) artery and percutaneous intervention in non-LAD arteries with contemporary drug-eluting stents. The composite primary endpoint included MACCE (major adverse cardiac and cerebrovascular events: death, myocardial infarction, stroke, and repeated revascularization) in long-term observation. The study cohort consisted of 30 patients (68% male) with stable coronary artery disease (26.7%) and unstable angina (73.3%). Procedural success was 100%. No death, myocardial infarction (MI), or stroke were observed in the perioperative period. One patient (3.3%) required chest revision and blood transfusion due to surgical bleeding. Kidney injury was noted in two patients (6.6%). In a long-term follow-up (median; IQR: 4.25; 2.62-4.69 years), two patients (6.6%) underwent repeated revascularization and one patient (3.3%) died due to MI. The overall primary endpoint rate was 9.9%. Conclusion: One-stage hybrid revascularization, on DAPT, is a feasible, safe, and efficient way of achieving complete revascularization in selected patients. The complication rate is low and acceptable. Further randomized trials are required. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2022 Sanetra, Buszman, Jankowska-Sanetra, Cisowski, Fil, Gorycki, Bochenek, Slabon-Turska, Konopko, Kaźmierczak, Gerber, Milewski and Buszman.)
Databáze:	MEDLINE
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