Effect of Auricular Acupoint Bloodletting plus Auricular Acupressure on Sleep Quality and Neuroendocrine Level in College Students with Primary Insomnia: A Randomized Controlled Trial.

Autor: Chen H; College of Acupuncture Moxibustion and Massage, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China.; International Joint Research Center for Preponderant Diseases of Acupuncture in Hebei Province, Shijiazhuang, 050200, China., Zhang MJ; College of Acupuncture Moxibustion and Massage, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China., Wu JA; College of Acupuncture Moxibustion and Massage, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China., She YF; College of Acupuncture Moxibustion and Massage, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China. sheyanfen@163.com.; International Joint Research Center for Preponderant Diseases of Acupuncture in Hebei Province, Shijiazhuang, 050200, China. sheyanfen@163.com., Yuan XR; College of Acupuncture Moxibustion and Massage, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China., Huo YX; College of Acupuncture Moxibustion and Massage, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China., Sun H; College of Acupuncture Moxibustion and Massage, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China., Liu DN; College of Acupuncture Moxibustion and Massage, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China., Shi XL; College of Acupuncture Moxibustion and Massage, Hebei University of Chinese Medicine, Shijiazhuang, 050200, China.
Jazyk: angličtina
Zdroj: Chinese journal of integrative medicine [Chin J Integr Med] 2022 Dec; Vol. 28 (12), pp. 1096-1104. Date of Electronic Publication: 2022 Nov 03.
DOI: 10.1007/s11655-022-3581-0
Abstrakt: Objective: To evaluate the effects of auricular acupoint bloodletting (AB) and auricular acupressure (AA) on sleep quality and the levels of melatonin (MT), glutamic acid (Glu), and γ -aminobutyric acid (GABA) in college students with primary insomnia, and to explore the possible mechanism.
Methods: Totally 74 college students at Hebei University of Chinese Medicine with primary insomnia were selected from October 2019 to October 2020. All patients were assigned to AB+AA group (37 cases, received combination of AB and AA) and AA group (37 cases, received only AA on the same acupoints) by a random number table. Each group was treated twice a week for 4 weeks. The Pittsburgh Sleep Quality Index (PSQI) score, Chinese medicine (CM) syndrome score, total effective rate, serum concentrations of MT, Glu, and GABA, and Glu/GABA ratio were compared between the two groups after treatment and at follow-up. The safety of therapy was also evaluated.
Results: After 4-week treatment, the total scores of PSQI, each PSQI component score, and the CM syndrome scores in both groups all decreased (P<0.05); the serum MT concentrations in both groups all increased (P<0.05). The concentrations of Glu and GABA in the AB+AA group were significantly higher than those in the AA group after treatment (P<0.05). However, there was no significant difference in the ratio of Glu/GABA in both groups before and after treatment (P>0.05). At follow-up, the CM syndrome score in the AB+AA group was significantly lower than that in the AA group (P<0.05). There was no significant difference between the two groups in total effective rates and adverse events (P>0.05).
Conclusions: Both AB+AA and AA can relieve insomnia symptoms, but a stronger long-term effect were observed for AB+AA. AB+AA can promote the secretion of MT, increase the levels of Glu and GABA more effective than AA, and regulate their imbalance, and thus it may be benificial for treating insomnia.
(© 2022. The Chinese Journal of Integrated Traditional and Western Medicine Press and Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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