Pleural metastasis from pulmonary primary signet-ring squamous cell carcinoma. Case report and literature review.

Autor: Torres-Rivas HE; Pathology Department, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain., Ariza-Prota M; Pulmonology Department, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain., González Gutiérrez MP; Pathology Department, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain., Berrios Hernández ML; Pathology Department, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain., Bravo Peláez B; Pathology Department, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain., Fernández Fernández LM; Pathology Department, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain.
Jazyk: angličtina
Zdroj: Diagnostic cytopathology [Diagn Cytopathol] 2023 Feb; Vol. 51 (2), pp. E65-E69. Date of Electronic Publication: 2022 Nov 01.
DOI: 10.1002/dc.25070
Abstrakt: Signet-ring cells are morphologically defined by the presence of a large intracytoplasmic vacuole that compresses and displaces the nucleus to the periphery. In most cases, these cells are associated with adenocarcinomas of various locations, and with non-epithelial neoplasms. To date, less than 20 cases of squamous cell carcinoma with signet-ring morphology have been described, mainly located on the skin. We present the case of a 73-year-old male with pleural effusion and a left lower lobe mass. The cytological study of the pleural effusion allowed the diagnosis of metastasis of squamous cell carcinoma, signet-ring cell variant. The treatment of lung cancer in advanced stages requires a precise diagnosis that allows the best therapy to be offered to the patient, depending on the clinical stage and the positivity of the biomarkers, among others. Our patient died 18 months after the initial diagnosis.
(© 2022 Wiley Periodicals LLC.)
Databáze: MEDLINE
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