Detection of SARS-COV-2 by functionally imprinted micelles.

Autor: Hubbard LR; Pacific Northwest National Laboratory, Richland, Washington, DC USA., Allen CJ; Pacific Northwest National Laboratory, Richland, Washington, DC USA., Sims AC; Pacific Northwest National Laboratory, Richland, Washington, DC USA., Engbrecht KM; Pacific Northwest National Laboratory, Richland, Washington, DC USA., O'Hara MJ; Pacific Northwest National Laboratory, Richland, Washington, DC USA., Johnson JC; Pacific Northwest National Laboratory, Richland, Washington, DC USA., Morrison SS; Pacific Northwest National Laboratory, Richland, Washington, DC USA.
Jazyk: angličtina
Zdroj: MRS communications [MRS Commun] 2022; Vol. 12 (6), pp. 1160-1167. Date of Electronic Publication: 2022 Oct 25.
DOI: 10.1557/s43579-022-00242-0
Abstrakt: The near real-time detection of airborne particles-of-interest is needed for avoiding current/future threats. The incorporation of imprinted particles into a micelle-based electrochemical cell produced a signal when brought into contact with particle analytes (such as SARS-COV-2), previously imprinted onto the structure. Nanoamp scales of signals were generated from what may've been individual virus-micelle interactions. The system showed selectivity when tested against similar size and morphology particles. The technology was compatible with airborne aerosol sampling techniques. Overall, the application of imprinted micelle technology could provide near real-time detection methods to a host of possible analytes of interest in the field.
Supplementary Information: The online version contains supplementary material available at 10.1557/s43579-022-00242-0.
Competing Interests: Conflict of interestOn behalf of all authors, the corresponding author states that there is no conflict of interest.
(© Battelle Memorial Institute, under exclusive license to The Materials Research Society 2022, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.)
Databáze: MEDLINE