Rapid ventricular tachycardia in patients with tetralogy of Fallot and implantable cardioverter-defibrillator: Insights from the DAI-T4F nationwide registry.

Autor: Laredo M; Unité de Rythmologie, Cardiology institute, Sorbonne University, AP-HP, La Pitié-Salpêtrière University Hospital, Paris, France., Duthoit G; Unité de Rythmologie, Cardiology institute, Sorbonne University, AP-HP, La Pitié-Salpêtrière University Hospital, Paris, France., Sacher F; LIRYC Institute, Bordeaux University Hospital, Bordeaux, France., Anselme F; Rouen University Hospital, Rouen, France., Audinet C; Bretagne Sud Hospital, Lorient, France., Bessière F; Louis Pradel Hospital, Lyon, France., Bordachar P; LIRYC Institute, Bordeaux University Hospital, Bordeaux, France., Bouzeman A; Parly II Private Hospital, Le Chesnay, France., Boveda S; Pasteur Clinic, Toulouse, France., Bun SS; Princess Grace Hospital, Monaco, France., Chassignolle M; Université de Paris, INSERM, Paris Cardiovascular Research Centre, Paris, France., Clerici G; Saint Pierre University Hospital, La Réunion, France., Da Costa A; Saint Etienne University Hospital, Saint Etienne, France., de Guillebon M; Pau Hospital, Pau, France., Defaye P; Grenoble University Hospital, Grenoble, France., Elbaz N; Henri-Mondor University Hospital, Créteil, France., Eschalier R; Clermont Ferrand University Hospital, Clermont Ferrand, France., Extramiana F; Bichat University Hospital, Paris, France., Fauchier L; Tours University Hospital, Tours, France., Hermida A; Amiens University Hospital, Amiens, France., Gandjbakhch E; Unité de Rythmologie, Cardiology institute, Sorbonne University, AP-HP, La Pitié-Salpêtrière University Hospital, Paris, France., Garcia R; Poitiers University Hospital, Poitiers, France., Gourraud JB; Nantes University Hospital, Nantes, France., Guenancia C; Dijon University Hospital, Dijon, France., Guy-Moyat B; Limoges University Hospital, Limoges, France., Irles D; Annecy Hospital, Annecy, France., Iserin L; Adult Congenital Heart Disease Medico-Surgical Unit, European Georges Pompidou Hospital, Paris, France., Jourda F; Auxerre Hospital, Auxerre, France., Koutbi L; La Timone Hospital, Marseille, France., Labombarda F; Caen University Hospital, Caen, France., Ladouceur M; Université de Paris, INSERM, Paris Cardiovascular Research Centre, Paris, France; Adult Congenital Heart Disease Medico-Surgical Unit, European Georges Pompidou Hospital, Paris, France., Lagrange P; Saint-Pierre Clinic, Perpignan, France., Lellouche N; Henri-Mondor University Hospital, Créteil, France., Mansourati J; Brest University Hospital, Brest, France., Marquié C; Lille University Hospital, Lille, France., Martins R; Rennes University Hospital, Rennes, France., Massoulié G; Clermont Ferrand University Hospital, Clermont Ferrand, France., Mathiron A; Amiens University Hospital, Amiens, France., Maury P; Toulouse University Hospital, Toulouse, France., Messali A; Bichat University Hospital, Paris, France., Milhem A; La Rochelle Hospital, La Rochelle, France., Mondoly P; Toulouse University Hospital, Toulouse, France., Nguyen C; Chalon sur Saône Hospital, Chalon sur Saône, France., Ninni S; Lille University Hospital, Lille, France., Pasquié JL; Montpellier University Hospital, Montpellier, France., Pierre B; Tours University Hospital, Tours, France., Pujadas P; Les Franciscaines Clinic, Nîmes, France., Sellal JM; Nancy University Hospital, Nancy, France., Thambo JB; LIRYC Institute, Bordeaux University Hospital, Bordeaux, France., Walton C; Louis Pradel Hospital, Lyon, France., Winum P; Nîmes University Hospital, Nîmes, France., Zakine C; Saint-Gatien Clinic, Tours, France., Zhao A; Ambroise Paré Clinic, Neuilly, France., Jouven X; Université de Paris, INSERM, Paris Cardiovascular Research Centre, Paris, France; Cardiac Electrophysiology Section, European Georges Pompidou Hospital, Paris, France., Combes N; Pasteur Clinic, Toulouse, France., Marijon E; Université de Paris, INSERM, Paris Cardiovascular Research Centre, Paris, France; Cardiac Electrophysiology Section, European Georges Pompidou Hospital, Paris, France., Waldmann V; Université de Paris, INSERM, Paris Cardiovascular Research Centre, Paris, France; Adult Congenital Heart Disease Medico-Surgical Unit, European Georges Pompidou Hospital, Paris, France; Cardiac Electrophysiology Section, European Georges Pompidou Hospital, Paris, France. Electronic address: victor.waldmann@gmail.com.
Jazyk: angličtina
Zdroj: Heart rhythm [Heart Rhythm] 2023 Feb; Vol. 20 (2), pp. 252-260. Date of Electronic Publication: 2022 Oct 26.
DOI: 10.1016/j.hrthm.2022.10.016
Abstrakt: Background: In repaired tetralogy of Fallot (TOF), little is known about characteristics of patients with rapid ventricular tachycardia (VT). Also, whether patients with a first episode of nonrapid VT may subsequently develop rapid VT or ventricular fibrillation (VF) has not been addressed.
Objectives: The objectives of this study were to compare patients with rapid VT/VF with those with nonrapid VT and to assess the evolution of VT cycle lengths (VTCLs) overtime.
Methods: Data were analyzed from a nationwide registry including all patients with TOF and implantable cardioverter-defibrillator (ICD) since 2000. Patients with ≥1 VT episode with VTCL ≤250 ms (240 beats/min) formed the rapid VT/VF group.
Results: Of 144 patients (mean age 42.0 ± 12.7 years; 104 [72%] men), 61 (42%) had at least 1 VT/VF episode, including 28 patients with rapid VT/VF (46%), during a median follow-up of 6.3 years (interquartile range 2.2-10.3 years). Compared with patients in the nonrapid VT group, those in the rapid VT/VF group were significantly younger at ICD implantation (35.2 ± 12.6 years vs 41.5 ± 11.2 years; P = .04), had more frequently a history of cardiac arrest (8 [29%] vs 2 [6%]; P = .02), less frequently a history of atrial arrhythmia (11 [42%] vs 22 [69%]; P = .004), and higher right ventricular ejection fraction (43.3% ± 10.3% vs 36.6% ± 11.2%; P = .04). The median VTCL of VT/VF episodes was 325 ms (interquartile range 235-429 ms). None of the patients with a first documented nonrapid VT episode had rapid VT/VF during follow-up.
Conclusion: Patients with TOF and rapid VT/VF had distinct clinical characteristics. The relatively low variation of VTCL over time suggests a room for catheter ablation without a backup ICD in selected patients with well-tolerated VT.
(Copyright © 2022 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE