Reliability, validity, and responsiveness of the Japanese version of the EORTC QLQ-ELD14 in evaluating the health-related quality of life of elderly patients with cancer.

Autor: Kinoshita Y; School of Nursing, Faculty of Medicine, University of Miyazaki, 5200 Kiyotakecho Kihara, Miyazaki, 889-1692, Japan. yumiko_kinoshita@med.miyazaki-u.ac.jp.; Department of Health Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. yumiko_kinoshita@med.miyazaki-u.ac.jp., Izukura R; Department of Basic Medicine, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan., Kishimoto J; Center of Clinical and Translational Research, Kyushu University Hospital, Fukuoka, Japan., Kanaoka M; School of Nursing, Faculty of Medicine, University of Miyazaki, 5200 Kiyotakecho Kihara, Miyazaki, 889-1692, Japan., Fujita H; Department of Surgery, Japan Community Health Care Organization Fukuoka Central Yutaka Hospital, Fukuoka, Japan.; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Ando K; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Nagai S; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.; Department of Surgery, Kitakyushu Municipal Medical Center, Fukuoka, Japan., Akiyoshi S; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Tagawa T; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.; Department of Thoracic Surgery, Clinical Research Institute, National Hospital Organization, Kyushu Medical Center, Fukuoka, Japan., Kubo M; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Inokuchi J; Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Ohuchida K; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Oki E; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Tanaka K; Department of Respiratory Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Eto M; Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Yoshizumi T; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Nakamura M; Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Chishaki A; Department of Health Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.; Faculty of Nursing, Fukuoka Nursing College, Fukuoka, Japan.
Jazyk: angličtina
Zdroj: Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2023 Jul; Vol. 149 (8), pp. 4899-4914. Date of Electronic Publication: 2022 Oct 28.
DOI: 10.1007/s00432-022-04414-2
Abstrakt: Purpose: This study evaluated the reliability, validity, and responsiveness of the Japanese version of the European Organization for Research and Treatment of Cancer (EORTC) QLQ-ELD14 and measured the health-related quality of life (HRQOL) of elderly Japanese patients with cancer aged ≥ 60 and ≥ 70 years.
Methods: The study recruited elderly Japanese patients with cancer aged ≥ 60 (≥ 70) years (n = 1803 [n = 1236]). The EORTC QLQ-ELD14 was evaluated for reliability, validity, responsiveness, and correlations of changes in score between the EORTC QLQ-ELD14 and the EORTC QLQ-C30 before and after the commencement of the COVID-19 pandemic.
Results: In both age groups, the proportion of missing items was low (< 3%). Cronbach's α was good at ≥ 0.70, except for two of the seven items. All the intraclass coefficient constants were good at ≥ 0.70. The concurrent validity was good but correlation with the EORTC QLQ-C30 was not strong, except for the hypothesis items. Regarding the assessment of responsiveness, only one item ("maintaining purpose") of the EORTC QLQ-ELD14 worsened (- 6.14 ± 29.20, standard response of mean > 0.2) after the commencement of the COVID-19 pandemic. The changes in score between the EORTC QLQ-ELD14 and the "global health status/QOL" and "summary score" of the EORTC QLQ-C30 had moderate-to-high negative correlations for all items, except two. Hypotheses to evaluate construct validity were accepted at 90%, while responsiveness was accepted at 80%.
Conclusion: The Japanese version of the EORTC QLQ-ELD14 questionnaire appears to have acceptable reliability, validity, and responsiveness to evaluate HRQOL in elderly Japanese people with cancer.
(© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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