Balamuthia mandrillaris brain infection: a rare cause of a ring-enhancing central nervous system lesion. Illustrative case.
| Autor: | Levinson S; Departments of1Neurosurgery and., Kumar KK; Departments of1Neurosurgery and., Wang H; 2Pathology, and., Tayyar R; 3Division of Infectious Diseases and Geographic Medicine, Stanford University, Palo Alto, California., Dunning M; 3Division of Infectious Diseases and Geographic Medicine, Stanford University, Palo Alto, California., Toland A; 2Pathology, and., Budvytiene I; 2Pathology, and., Vogel H; 2Pathology, and., Chang A; 3Division of Infectious Diseases and Geographic Medicine, Stanford University, Palo Alto, California., Banaei N; 2Pathology, and., Shuer L; Departments of1Neurosurgery and. |
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| Jazyk: | angličtina |
| Zdroj: | Journal of neurosurgery. Case lessons [J Neurosurg Case Lessons] 2022 Apr 11; Vol. 3 (15). Date of Electronic Publication: 2022 Apr 11 (Print Publication: 2022). |
| DOI: | 10.3171/CASE2268 |
| Abstrakt: | Background: An 80-year-old man presented with subacute mental status change, dizziness, and left-sided vision loss. Magnetic resonance imaging demonstrated a ring-enhancing right parietooccipital lesion. Observations: Biopsy and laboratory testing demonstrated an amoebic Balamuthia mandrillaris infection. Fewer than 200 cases of this infection have been recognized in the United States, and no standardized treatment regimen currently exists. Lessons: Rapid antimicrobial therapy with miltefosine, azithromycin, fluconazole, flucytosine, sulfadiazine, and albendazole was initiated. The pathophysiology, diagnosis, and management of this infection and the patient's course were reviewed. The importance of biopsy for pathologic and laboratory diagnosis and rapid treatment initiation with a multidisciplinary team was reinforced. |
| Databáze: | MEDLINE |
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