Encephalopathy With Akinetic Mutism in a Child With COVID-19 Infection: A Case Report.

Autor:	Jewell T; University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Arendt D; University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Haffley K; Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Beversdorf A; Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., St Clair NE; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Hsu D; Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, hsu@neurology.wisc.edu.
Jazyk:	angličtina
Zdroj:	WMJ : official publication of the State Medical Society of Wisconsin [WMJ] 2022 Oct; Vol. 121 (3), pp. E42-E45.
Abstrakt:	Introduction: COVID-19 has been associated with neurological complications, including encephalopathy and akinetic mutism. Case Presentation: A 7-year-old unvaccinated boy presented with visual hallucinations, urinary incontinence, and akinetic mutism 13 days after he was exposed to COVID-19. He had minimal respiratory symptoms, including just 1 day of fever and cough. Evaluations showed slowing on electroencephalogram, normal cerebrospinal fluid, normal brain magnetic resonance imaging, and mild sinus bradycardia. He recovered rapidly to baseline after 5 days of intravenous methylprednisolone. Discussion: COVID-19-related encephalopathy including akinetic mutism is usually found in older adult patients with more severe COVID-19 illness. Our case demonstrates that akinetic mutism can present in children with mild COVID-19 illness and that it can respond rapidly and completely to intravenous methylprednisolone. Conclusions: COVID-19-related encephalopathy may be immune mediated. A heightened awareness of its association with COVID-19 illness should lead to earlier diagnosis and consideration of immunomodulatory therapy. (Copyright© Board of Regents of the University of Wisconsin System and The Medical College of Wisconsin, Inc.)
Databáze:	MEDLINE
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