Comparative Effectiveness of Coronary Artery Bypass Graft Surgery and Percutaneous Coronary Intervention for Patients With Coronary Artery Disease: A Meta-Analysis of Randomized Clinical Trials.

Autor:	Shaik TA; Cardiovascular Medicine, University of Louisville School of Medicine, Louisville, USA., Chaudhari SS; General Practice, Lions General Hospital, Mehsana, IND.; General Practice, General Hospital, Vadnagar, IND., Haider T; Internal Medicine, District Headquarter Hospital, Lahore, PAK., Rukia R; Medical Student, Liaquat University of Medical and Health Sciences, Hyderabad, PAK., Al Barznji S; Internal Medicine, University of Sulaymaniyah, Sulaymaniyah, IRQ., Kataria H; Internal Medicine, Government Medical College, Surat, Surat, IND., Nepal L; Internal Medicine, Kathmandu Medical College and Teaching Hospital, Kathmandu, NPL., Amin A; Cardiology, Pakistan Navy Station Shifa, Karachi, PAK.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2022 Sep 23; Vol. 14 (9), pp. e29505. Date of Electronic Publication: 2022 Sep 23 (Print Publication: 2022).
DOI:	10.7759/cureus.29505
Abstrakt:	Percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) surgery are the options for revascularization in coronary artery disease (CAD). This meta-analysis aims to compare the efficacy of CABG and PCI for the management of patients with CAD. The meta-analysis was conducted as per the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Cochrane Library, and EMBASE were searched for relevant articles. The reference list of included articles was also searched manually for additional publications. Primary endpoints were cardiovascular mortality and all-cause mortality. Secondary endpoints included myocardial infarction, stroke, and revascularization. In total, 12 randomized control trials (RCTs) were included in this meta-analysis encompassing 9,941 patients (4,954 treated with CABG and 4,987 with PCI). The analysis showed that PCI was associated with a higher risk of all-cause mortality (risk ratio (RR) = 1.26, 95% confidence interval (CI) = 1.10-1.45) and revascularization (RR = 2.42, 95% CI = 1.82-3.21). However, no significant differences were reported between two arms regarding cardiovascular mortality (RR = 1.15, 95% CI = 0.96-1.39), myocardial infarction (RR = 1.17, 95% CI = 0.82-1.67), and stroke (RR = 0.64, 95% CI = 0.35-1.16). CABG was associated with a significant reduction in all-cause mortality and revascularization compared to PCI. However, no significant difference was reported in the risk of cardiovascular mortality, myocardial infarction, and stroke between the two groups. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Shaik et al.)
Databáze:	MEDLINE
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