Does Abdominal Obesity Increase All-Cause, Cardiovascular Disease, and Cancer Mortality Risks in Older Adults? A 10-Year Follow-Up Analysis.

Autor: Moura LANE; Graduate Program in Health Sciences, Medicine Faculty, Federal University of Goiás, Goiânia 74605-050, GO, Brazil., Pagotto V; Graduate Program in Nursing, Nursing Faculty, Federal University of Goiás, Goiânia 74605-080, GO, Brazil., Camargo Pereira C; Graduate Program in Health Sciences, Medicine Faculty, Federal University of Goiás, Goiânia 74605-050, GO, Brazil., de Oliveira C; Department of Epidemiology and Public Health, Institute of Epidemiology and Health Care, University College London, London WC1E 6BT, UK., Silveira EA; Graduate Program in Health Sciences, Medicine Faculty, Federal University of Goiás, Goiânia 74605-050, GO, Brazil.; Department of Epidemiology and Public Health, Institute of Epidemiology and Health Care, University College London, London WC1E 6BT, UK.
Jazyk: angličtina
Zdroj: Nutrients [Nutrients] 2022 Oct 15; Vol. 14 (20). Date of Electronic Publication: 2022 Oct 15.
DOI: 10.3390/nu14204315
Abstrakt: There is insufficient evidence on the impact of abdominal obesity (AO) on mortality in older adults. Therefore, the objective to analyze the 10-year impact of AO, assessed using different diagnostic criteria, on all-cause, cardiovascular disease (CVD), and cancer mortality in older adults. In this prospective cohort study of older adults (≥60 years), sociodemographic, lifestyle, clinical history, laboratory test, and anthropometric data were analyzed. The considered were used for AO diagnostic: waist circumference (WC) of ≥88 cm for women and ≥102 cm for men; WC of ≥77.8 cm for women and ≥98.8 cm for men; and increased waist-to-hip ratio (WHR), being the highest tertile of distribution by sex. Multivariate Cox regression and Kaplan-Meier analyses were performed. A total of 418 individuals, with an average age of 70.69 ± 7.13 years, participated in the study. In the analysis adjusted for sex and age, WHR was associated with a high risk of all-cause mortality ( p = 0.044). Both cutoff points used for the WC were associated with an increased CVD mortality risk. None of the AO parameters were associated with cancer mortality. An increased WHR was associated to a higher all-cause mortality risk factor, while an increased WC was a risk factor for a higher CVD mortality in older adults.
Databáze: MEDLINE