Autor: |
Cocuz IG; Doctoral School of Medicine and Pharmacy, University of Medicine, Pharmacy, Sciences and Technology 'George Emil Palade' of Targu Mures, 540142 Targu Mures, Romania.; Pathology Department, Mures Clinical County Hospital, 540011 Targu Mures, Romania.; Pathophysiology Department, University of Medicine, Pharmacy, Sciences and Technology 'George Emil Palade' of Targu Mures, 540142 Targu Mures, Romania., Cocuz ME; Fundamental Prophylactic and Clinical Disciplines Department, Faculty of Medicine, Transilvania University of Brasov, 500003 Brașov, Romania.; Clinical Infectious Diseases Hospital of Brasov, 500174 Brasov, Romania., Repanovici A; Faculty of Product Design and Environment, Transilvania University of Brasov, 500036 Brasov, Romania., Sabău AH; Pathology Department, Mures Clinical County Hospital, 540011 Targu Mures, Romania.; Pathophysiology Department, University of Medicine, Pharmacy, Sciences and Technology 'George Emil Palade' of Targu Mures, 540142 Targu Mures, Romania., Niculescu R; Pathology Department, Mures Clinical County Hospital, 540011 Targu Mures, Romania.; Pathophysiology Department, University of Medicine, Pharmacy, Sciences and Technology 'George Emil Palade' of Targu Mures, 540142 Targu Mures, Romania., Tinca AC; Pathology Department, Mures Clinical County Hospital, 540011 Targu Mures, Romania.; Pathophysiology Department, University of Medicine, Pharmacy, Sciences and Technology 'George Emil Palade' of Targu Mures, 540142 Targu Mures, Romania., Vunvulea V; Anatomy and Embryology Department, University of Medicine, Pharmacy, Sciences and Technology 'George Emil Palade' of Targu Mures, 540142 Targu Mures, Romania., Budin CE; Pathophysiology Department, University of Medicine, Pharmacy, Sciences and Technology 'George Emil Palade' of Targu Mures, 540142 Targu Mures, Romania., Szoke AR; Pathology Department, Mures Clinical County Hospital, 540011 Targu Mures, Romania.; Pathophysiology Department, University of Medicine, Pharmacy, Sciences and Technology 'George Emil Palade' of Targu Mures, 540142 Targu Mures, Romania., Popelea MC; Pathology Department, Mures Clinical County Hospital, 540011 Targu Mures, Romania., Moraru R; Anatomy and Embryology Department, University of Medicine, Pharmacy, Sciences and Technology 'George Emil Palade' of Targu Mures, 540142 Targu Mures, Romania.; Department of Plastic Surgery, Mures Clinical County Hospital, 540011 Targu Mures, Romania., Cotoi TC; Pharmaceutical Technique Department, University of Medicine, Pharmacy, Sciences and Technology 'George Emil Palade' of Targu Mures, 540142 Targu Mures, Romania.; Pharmacy No. 2, Mures Clinical County Hospital, 540011 Targu Mures, Romania., Cotoi OS; Pathology Department, Mures Clinical County Hospital, 540011 Targu Mures, Romania.; Pathophysiology Department, University of Medicine, Pharmacy, Sciences and Technology 'George Emil Palade' of Targu Mures, 540142 Targu Mures, Romania. |
Abstrakt: |
Introduction: Cutaneous squamous cell carcinoma (cSCC) is one of the most frequently occurring types of cancer in humans. Scientometric research is an innovative method for analyzing the research trends in various domains, with great implications in the field of medicine. Materials and Methods: We searched the Web of Science database with the following established query terms: "Squamous cell carcinoma", "skin", and "immunohistochemistry". After applying the inclusion and exclusion criteria, a total of 76 articles were selected. The present study aims to analyze, based on the frequency of use of keywords with scientometric algorithms and map-based distributions, the trends of the research concerning cSCCs in 2017-2022. Results: A graphical representation based on 11 scientometric maps presented the division of the keywords into seven clusters, from which seven categories of research interest were defined. The clusters represent a multidisciplinary approach to the diagnosis and treatment of cSCCs, cancer diagnostics, patient outcomes, histopathological importance, management of cSCCs, role of progression, and adequate treatment of and importance of immunohistochemistry for cSCCs. The distribution of the citations shows the importance of the available research on cSCCs by analyzing the first five most-cited articles included in our study in direct concordance with the seven defined clusters. Conclusion: The scientometric research method reveals the interest of research in the multidisciplinary approach used to obtain the best outcomes for the patient, including a targeted investigation, as well as diagnostic and treatment options. The trends in the research reveal that histopathological diagnostics and immunohistochemistry, combined with molecular techniques, are the most important tools used to establish a personalized diagnosis, thus increasing the quality of life and life expectancy for patients with cSCCs. |