Ascites as First Atypical and Only Clinical Manifestation of De Novo Follicular Lymphoma.

Autor: Zdravkovic ND; Faculty of Medical Sciences, Department of Internal Medicine, University of Kragujevac, 34000 Kragujevac, Serbia.; Clinic of Gastroenterohepatology, University Clinical Center, 34000 Kragujevac, Serbia., Grbovic VM; Faculty of Medical Sciences, Department of Physical Medicine and Rehabilitation, University of Kragujevac, 34000 Kragujevac, Serbia.; Clinic of Physical Medicine and Rehabilitation, University Clinical Center, 34000 Kragujevac, Serbia., Vojinovic RH; Faculty of Medical Sciences, Department of Radiology, University of Kragujevac, 34000 Kragujevac, Serbia.; Clinic of Radiology, University Clinical Center, 34000 Kragujevac, Serbia., Stolic RV; Faculty of Medical Sciences, Department of Internal Medicine, University of Kragujevac, 34000 Kragujevac, Serbia.; Clinic of Nephrology, University Clinical Center, 34000 Kragujevac, Serbia., Zivic JZ; Faculty of Medical Sciences, Department of Internal Medicine, University of Kragujevac, 34000 Kragujevac, Serbia.; Clinic of Gastroenterohepatology, University Clinical Center, 34000 Kragujevac, Serbia., Maksic MM; Clinic of Gastroenterohepatology, University Clinical Center, 34000 Kragujevac, Serbia., Zivic ZP; Clinic of Gastroenterohepatology, University Clinical Center, 34000 Kragujevac, Serbia., Andjelkovic NV; Faculty of Medical Sciences, Department of Internal Medicine, University of Kragujevac, 34000 Kragujevac, Serbia.; Clinic of Hematology, University Clinical Center, 34000 Kragujevac, Serbia., Zivic MZ; Faculty of Medical Sciences, Department of Dentistry, University of Kragujevac, 34000 Kragujevac, Serbia., Todorovic ZD; Faculty of Medical Sciences, Department of Internal Medicine, University of Kragujevac, 34000 Kragujevac, Serbia.; Clinic of Hematology, University Clinical Center, 34000 Kragujevac, Serbia.
Jazyk: angličtina
Zdroj: Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2022 Oct 01; Vol. 58 (10). Date of Electronic Publication: 2022 Oct 01.
DOI: 10.3390/medicina58101381
Abstrakt: Follicular lymphoma is the most common indolent non-Hodgkin's lymphoma and is usually initially detected in lymph nodes. Primary extranodal NHL is most commonly primarily localized in the gastrointestinal tract. We present one unusual case of ileum FL with ascites as the first clinical sign. The 73-year-old female patient was presented to the emergency department for evaluation of mild abdominal pain and abdominal swelling that had been going on for three days followed by bloating and occasional pain in the spine. The abdominal contrast-enhanced CT revealed the contrast stagnation in the distal part of the ileum. The ileum wall about 11 cm in length was thickened up to 2.9 cm and the tumor mass infiltrated all layers of ileum mesenteric lymphadenopathy up to 2 cm in diameter and significant ascites. On the upper ileum wall, the vegetative mass was described 3 cm in diameter. The patient had an emergent laparotomy with the ileocolic resection and latero-lateral ileocolic anastomosis. The microscopy finding of terminal ileum and the regional lymph nodes showed domination of cleaved cells with irregular nuclei which correspond to centrocytes. There were 0-15 large non-cleaved cells corresponding to centroblast in the microscopy high-power field. The final diagnosis was follicular lymphoma, the clinical stage 2E and histological grade by Berard and Mann criteria 1-2.
Databáze: MEDLINE
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