Cervical and Endometrial Cancer Incidence in the Female Population from the Bryansk Region Living in Conditions of Chemical, Radioactive and Combined Environmental Contamination (2000-2020).

Autor: Korsakov AV; Department of Disaster Medicine, Faculty of Medicine, Pirogov Russian National Research Medical University (Pirogov Medical University), 117997 Moscow, Russia., Kryukova AE; Department of Technosphere Safety, Bryansk State Technical University, 241035 Bryansk, Russia., Troshin VP; Department of Technosphere Safety, Bryansk State Technical University, 241035 Bryansk, Russia., Milushkina OY; Department of Hygiene, Faculty of Pediatrics, Pirogov Russian National Research Medical University (Pirogov Medical University), 117997 Moscow, Russia., Lagerev DG; Department of Computer Science and Software, Bryansk State Technical University, 241035 Bryansk, Russia.
Jazyk: angličtina
Zdroj: Life (Basel, Switzerland) [Life (Basel)] 2022 Sep 25; Vol. 12 (10). Date of Electronic Publication: 2022 Sep 25.
DOI: 10.3390/life12101488
Abstrakt: At the end of 36 years after the Chernobyl disaster, about 5 million people still live in the radioactively contaminated territories of Russia, Ukraine, and Belarus, and the density of radioactive contamination by Cesium-137 and Strontium-90 will remain radiologically significant for decades. We assessed cervical and endometrial cancer primary incidence (new cases) in the female population from the Bryansk region living in conditions of chemical, radioactive, and combined environmental contamination for 2000−2020. We found a significant increase in the long-term trend in the primary incidence of cervical and endometrial cancer in all the studied groups, regardless of the environmental conditions of residence (p < 0.00001). We did not find statistically significant differences in the incidence of cervical and endometrial cancer in women, regardless of the level of chemical, radioactive, and combined environmental contamination. However, women living in environmentally unfavorable areas (in total, in the territories of chemical, radioactive, and combined contamination) are statistically significantly more likely to develop endometrial cancer in terms of relative risk compared to environmentally safe (control) areas (RR 1.17 (1.08−1.27)). No such pattern was found for cervix cancer. It should be noted, since environmentally safe (control) areas have a certain level of contamination (albeit low), RR is underestimated.
Databáze: MEDLINE
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