Initial management of acute hyperammonemia in pediatrics.
| Autor: | Eiroa H; Department of Inborn Errors of Metabolism, Hospital de Pediatría S.A.M.I.C. Prof. Dr. J. P. Garrahan, City of Buenos Aires, Argentina., Durand C; Laboratorio Chamoles, City of Buenos Aires, Argentina., Szlago M; Hospital de Niños Dr. Ricardo Gutiérrez, City of Buenos Aires, Argentina., Pereyra M; Department of Growth and Development, Hospital Pediátrico Dr. H. J. Notti, Mendoza, Argentina., Nuñez M; Unit of Metabolism, Hospital de Niños Sor María Ludovica, La Plata, Argentina., Guelbert N; Department of Metabolic Disorders, Clínica Universitaria Reina Fabiola, Universidad Católica de Córdoba, Córdoba, Argentina., Pacheco G; Program for Neonatal Screening and Uncommon Diseases, Ministry of Public Health of Salta, Salta, Argentina., Kleppe S; Area of Inborn Errors of Metabolism, Hospital Italiano de Buenos Aires, City of Buenos Aires, Argentina. |
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| Jazyk: | English; Spanish; Castilian |
| Zdroj: | Archivos argentinos de pediatria [Arch Argent Pediatr] 2023 Jun 01; Vol. 121 (3), pp. e202202614. Date of Electronic Publication: 2022 Oct 27. |
| DOI: | 10.5546/aap.2022-02614.eng |
| Abstrakt: | Hyperammonemia is a medical emergency. There are no publications regarding the availability of resources, supplies, and knowledge necessary for the initial management of hyperammonemia by pediatricians in Argentina; however, according to the authors' experience, the necessary resources are not available all year round in a large portion of our territory. Based on such state of affairs, an international bibliographic review on this topic and the authors' experience, we developed a series of ecommendations for the initial pediatric management of this emergency, with the objective of reducing deficiencies, allowing adequate clinical suspicion leading to a timely diagnosis and emergency management and a rational use of pharmacological resources (some of which are costly) to reduce the morbidity and mortality associated with hyperammonemia. (Sociedad Argentina de Pediatría.) |
| Databáze: | MEDLINE |
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