| Autor: |
Rekhtina IG; National Medical Research Center for Hematology., Mendeleeva LP; National Medical Research Center for Hematology., Soboleva NP; National Medical Research Center for Hematology., Dubina IA; Pavlov First Saint Petersburg State Medical University., Pervakova MI; Pavlov First Saint Petersburg State Medical University., Lapin SV; Pavlov First Saint Petersburg State Medical University. |
| Jazyk: |
ruština |
| Zdroj: |
Terapevticheskii arkhiv [Ter Arkh] 2022 Jan 15; Vol. 94 (1), pp. 135-144. Date of Electronic Publication: 2022 Jan 15. |
| DOI: |
10.26442/00403660.2022.01.201326 |
| Abstrakt: |
Paraprotein is a laboratory biomarker of plasma cell tumors and other lymphoproliferative diseases. Its determination is necessary for diagnosing, monitoring and assessment of therapy effectiveness. The lecture presents the main methods of qualitative and quantative analysis of monoclonal proteins: gel electrophoresis, capillary electrophoresis, immunofixation and nephelometry features, possibilities and limitations are reviewed. The main sources of errors and artifacts during these studies are considered. Also the difficulties in the diagnosis and interpretation of the results of serum and urine tests are highlighted. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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