[Modern understanding of bronchial asthma with fixed airflow obstruction].

Autor: Kraposhina AY; Voino-Yasenetsky Krasnoyarsk State Medical University.; Regional Clinical Hospital., Sobko EA; Voino-Yasenetsky Krasnoyarsk State Medical University.; Regional Clinical Hospital., Demko IV; Voino-Yasenetsky Krasnoyarsk State Medical University.; Regional Clinical Hospital., Kacer AB; Voino-Yasenetsky Krasnoyarsk State Medical University., Kazmerchuk OV; Voino-Yasenetsky Krasnoyarsk State Medical University., Abramov YI; Voino-Yasenetsky Krasnoyarsk State Medical University.
Jazyk: ruština
Zdroj: Terapevticheskii arkhiv [Ter Arkh] 2021 Mar 15; Vol. 93 (3), pp. 337-342. Date of Electronic Publication: 2021 Mar 15.
DOI: 10.26442/00403660.2021.03.200661
Abstrakt: The review provides data on one of the phenotypes of severe bronchial asthma it is asthma with fixed airway obstruction. According to data published today, there is no single pathway for the formation of fixed airway obstruction in patients with severe asthma. Increasing knowledge of the pathophysiology of fixed airway obstruction, as well as identifying the most significant risk factors, is essential for the successful treatment of such patients. In addition, the development of fixed obstruction is associated with a worse and sometimes fatal prognosis. Expanding the existing views is also necessary to overcome the difficulties of differential diagnosis between bronchial asthma with fixed airway obstruction and bronchial asthma in combination with COPD. All this will optimize the approach to the management of patients with bronchial asthma to prevent the formation of fixed airway obstruction.
Databáze: MEDLINE