[Relationship of visceral obesity and coronary calcinosis in ischemic heart disease].

Autor:	Brel NK; Research Institute for Complex Issues of Cardiovascular Diseases., Gruzdeva OV; Research Institute for Complex Issues of Cardiovascular Diseases.; Kemerovo State Medical University., Kokov AN; Research Institute for Complex Issues of Cardiovascular Diseases., Masenko VL; Research Institute for Complex Issues of Cardiovascular Diseases., Dyleva YA; Research Institute for Complex Issues of Cardiovascular Diseases., Belik EV; Research Institute for Complex Issues of Cardiovascular Diseases., Barbarash OL; Research Institute for Complex Issues of Cardiovascular Diseases.; Kemerovo State Medical University.
Jazyk:	ruština
Zdroj:	Terapevticheskii arkhiv [Ter Arkh] 2021 Dec 15; Vol. 93 (12), pp. 1428-1434. Date of Electronic Publication: 2021 Dec 15.
DOI:	10.26442/00403660.2021.12.201277
Abstrakt:	Aim: To assess the relationship between the prevalence of visceral obesity (VO) and the severity of coronary calcification (CC) in patients with verified coronary artery disease (CAD). Materials and Methods: 125 patients with CAD were examined. Assessment of the morphometric characteristics of visceral adipose tissue (VAT) and CC was perform using multislice computed tomography (MSCT). The calcium index (CI) of the coronary arteries (CA) was determine by the Agatston method. Statistical analysis was perform using Statistica 10.0. Results: VO was detect in 82 (65.6%) patients with CAD. In the presence of VO, higher CC values were observed in the projection of the envelope (p=0.00014), right coronary (p=0.00002) arteries, total CI (p=0.0003), and the prevalence of massive CC. Correlation analysis showed the relationship between the area of VAT and the CC of all the studied localizations. According to the ROC analysis, VO is a significant predictor of massive CC (area under the ROC curve AUC 0.72, 95% CI 0.560.89), in contrast to body mass index BMI (AUC 0.56, 95% CI 0.310.82). Conclusion: The index of the ratio of VAT to subcutaneous adipose tissue (VAT/SAT), but not BMI, had a direct correlation with CC. Morphology of VAT may be a significant diagnostic sign of massive CC in patients with CAD, as a factor affecting treatment and prognosis.
Databáze:	MEDLINE
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