A Narrative Review of Ultrathin-strut Drug-eluting Stents: The Thinner the Better?

Autor: Grundeken MJ; Department of Cardiology, Amsterdam University Medical Centre - location AMC, Amsterdam, The Netherlands., Beijk MA; Department of Cardiology, Amsterdam University Medical Centre - location AMC, Amsterdam, The Netherlands.
Jazyk: angličtina
Zdroj: Heart international [Heart Int] 2021 Dec 21; Vol. 15 (2), pp. 84-93. Date of Electronic Publication: 2021 Dec 21 (Print Publication: 2021).
DOI: 10.17925/HI.2021.15.2.84
Abstrakt: Second-generation drug-eluting stents (DES) are considered standard of care for revascularization of patients undergoing percutaneous coronary intervention. Besides the polymer and antiproliferative drug used, the metallic backbone of DES is an attractive target for further development. Ultrathin-strut DES (≤70 μm strut thickness) are more flexible, have an improved trackability and crossability compared to conventional second-generation DES. Importantly, ultrathin-strut DES reduce the risk of in-stent restenosis, thereby decreasing the risk of angiographic and clinical restenosis. In this narrative review, we will discuss the clinical outcomes of the commercially available ultrathin-strut DES.
Competing Interests: Disclosures: Maik J Grundeken and Marcel AM Beijk have no financial or non-financial relationships or activities to declare in relation to this article.
(© Touch Medical Media 2021.)
Databáze: MEDLINE