Evaluation of genotoxicity and cytotoxicity of inhabitants of Vila Rural Água Viva, Brazil, exposed to agrochemicals using the micronucleus buccal cytome assay.

Autor: Bressiani PA; Academic of Chemical Engineering, Universidade Tecnológica Federal do Paraná (UTFPR), Campus Francisco Beltrão, Paraná, Brazil. Electronic address: pbressiani@alunos.utfpr.edu.br., Alves GL; Academic of Chemical Engineering, Universidade Tecnológica Federal do Paraná (UTFPR), Campus Francisco Beltrão, Paraná, Brazil. Electronic address: geicianelocalves@hotmail.com., de Marco IG; Academic of Chemical Engineering, Universidade Tecnológica Federal do Paraná (UTFPR), Campus Francisco Beltrão, Paraná, Brazil. Electronic address: inara@alunos.utfpr.edu.br., Biffi MT; Academic of Chemical Engineering, Universidade Tecnológica Federal do Paraná (UTFPR), Campus Francisco Beltrão, Paraná, Brazil. Electronic address: mariana_biffi@hotmail.com., Ishikawa S; Academic of Chemical Engineering, Universidade Tecnológica Federal do Paraná (UTFPR), Campus Francisco Beltrão, Paraná, Brazil. Electronic address: sabrinaishikawa1811@gmail.com., Manosso FC; Academic Department of Agricultural Sciences, Universidade Tecnológica Federal do Paraná (UTFPR), Campus Francisco Beltrão, Francisco Beltrão, Paraná, Brazil. Electronic address: fmanosso@utfpr.edu.br., Gomes EMV; Academic Department of Physics, Statistics and Mathematics, Universidade Tecnológica Federal do Paraná (UTFPR), Francisco Beltrão, Paraná, Brazil. Electronic address: eduardogomes@utfpr.edu.br., Pokrywiecki TS; Academic Department of Engineering, Universidade Tecnológica Federal do Paraná (UTFPR), Campus Francisco Beltrão, Francisco Beltrão, Paraná, Brazil. Electronic address: ticiane@utfpr.edu.br., Schmitz APO; Academic Department of Engineering, Universidade Tecnológica Federal do Paraná (UTFPR), Campus Francisco Beltrão, Francisco Beltrão, Paraná, Brazil. Electronic address: anapoliveira@utfpr.edu.br., Düsman E; Academic Department of Chemistry and Biology, Universidade Tecnológica Federal do Paraná (UTFPR), Campus Francisco Beltrão, Paraná, Brazil. Electronic address: edusman@utfpr.edu.br.
Jazyk: angličtina
Zdroj: Environmental toxicology and pharmacology [Environ Toxicol Pharmacol] 2022 Nov; Vol. 96, pp. 104002. Date of Electronic Publication: 2022 Oct 21.
DOI: 10.1016/j.etap.2022.104002
Abstrakt: The aim of this study was to carry out a pilot investigation, using a buccal micronucleus cytome assay, with the population of Vila Rural Água Viva (Francisco Beltrão, Paraná, Brazil), environmentally exposed to agrochemicals. The data shows statistically differences between the control group (not exposed) and the population of Vila Rural regarding the cytotoxicity and mutagenicity. There was no significant change between the average relative frequencies of these data whether divided between smokers and non-smokers, or practitioners of physical activities or not. It was also observed that age or time of exposure to agrochemicals did not show a linear relationship with the average relative frequencies of cytotoxicity and mutagenicity data. The work shows the presence of 2,4-D herbicide in water sample of community, then it is hoped that the results will assist in guiding the dangers to health and the environment from exposure to agrochemicals.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2022 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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