Metallic and metal oxide-derived nanohybrid as a tool for biomedical applications.

Autor: Mujahid MH; Department of Biotechnology, Parul Institute of Applied Sciences and Centre of Research for Development, Parul University, Vadodara, Gujarat, 391760, India., Upadhyay TK; Department of Biotechnology, Parul Institute of Applied Sciences and Centre of Research for Development, Parul University, Vadodara, Gujarat, 391760, India. Electronic address: tarun_bioinfo@yahoo.co.in., Khan F; Department of Biotechnology, Noida Institute of Engineering & Technology, Greater Noida 201306, India., Pandey P; Department of Biotechnology, Noida Institute of Engineering & Technology, Greater Noida 201306, India., Park MN; Department of Pathology, College of Korean Medicine, Kyung Hee University, Seoul 02447, South Korea., Sharangi AB; Department of Plantation, Spices, Medicinal & Aromatic Crops, BCKV-Agricultural University, Mohanpur, 741252 Nadia, West Bengal, India., Saeed M; Department of Biology, College of Sciences, University of Hail, PO BOX 2240, Hail, Saudi Arabia., Upadhye VJ; Department of Biotechnology, Parul Institute of Applied Sciences and Centre of Research for Development, Parul University, Vadodara, Gujarat, 391760, India., Kim B; Department of Pathology, College of Korean Medicine, Kyung Hee University, Seoul 02447, South Korea. Electronic address: bongleekim@khu.ac.kr.
Jazyk: angličtina
Zdroj: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Nov; Vol. 155, pp. 113791. Date of Electronic Publication: 2022 Oct 07.
DOI: 10.1016/j.biopha.2022.113791
Abstrakt: Nanotechnology covers a variety of scientific areas including chemistry, material science, physics, biomedicine, biology, and engineering. Metal nanohybrid with extraordinary properties is highly researched in comparison to bulky individual nanoparticles. Especially, metal and metal oxide nanoparticles are a new class of functional nanohybrids having broad, intriguing physio-chemical properties showing applications in nanoscience and biomedical research. Engineered inorganic nanoparticles have paved an essential component in the advancement of nanotechnologies. Synthesis is done through various physical, chemical, and biological methods with their special features and manipulation at the nano level in their physiochemical properties, controlling their shape, size, and surface functionality. Application of metal and metal oxide nanohybrid are discussed, including, gene delivery, theranostics, and catalysis. Due to the versatile application of nanohybrids, it can be used in the detection of tumors, cell tracking, and visualizing the specific region of disease. Development of accurate, multifunctional imaging and ambient data are indispensable for futuristic applications. Nanohybrids (NHs) can load therapeutic drugs in their sector of core and shell and have the ability to release them in a controlled and sequential manner of a delivery system. Novel nanohybrid with their multidimensional, integrated mechanistic property has also shown a great effect on environmental pollution control also. A proteomics and transcriptomics approach for the nanohybrid action of mechanism has been discussed and also includes limitations of MNHs and MONHs. The current manuscript critically reviewed several available recent kinds of literature and has the potential to offer a better understanding of metallic and metallic oxide nanohybrids having a multifunctional role in various biomedical applications.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2022 The Authors. Published by Elsevier Masson SAS.. All rights reserved.)
Databáze: MEDLINE
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