Electrocardiographic features in children with severe falciparum malaria at the University College Hospital, Ibadan.
| Autor: | Akinkunmi BF; Department of Paediatrics and Child Health, University of Medical Sciences, Ondo City, Nigeria., Ogunkunle OO; Department of Paediatrics, University College Hospital Ibadan, Nigeria., Akinbami FO; Department of Paediatrics, Niger Delta University Teaching Hospital Okolobiri, Nigeria., Orimadegun AE; Institute of Child Health University of Ibadan, Ibadan, Nigeria. |
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| Jazyk: | angličtina |
| Zdroj: | Research journal of health sciences [Res J Health Sci] 2022; Vol. 10 (3), pp. 198-206. Date of Electronic Publication: 2022 Sep 28. |
| DOI: | 10.4314/rejhs.v10i3.4 |
| Abstrakt: | Introduction: The high burden of Malaria morbidity and mortality in children is due to its potential to cause multi-organ dysfunction. There is however limited information on the specific electrocardiographic features in falciparum malaria in paediatric age group. Aim: To investigate the electrocardiographic (ECG) features in children with (complicated) severe falciparum malaria (SM) and acute uncomplicated malaria (AUM) at the University College Hospital, Ibadan. Methods: This was a comparative cross-sectional study conducted among 398 children with symptomatic and confirmed Plasmodium falciparum malaria and apparently healthy controls. The frequencies of ECG features were described and compared among these children. Results: The prevalence of ECG abnormality was 79.7% and 63.2% in Severe Malaria SM and Acute uncomplicated malaria AUM patients, respectively. Sinus tachycardia was significantly more frequent in SM than AUM and control groups (p <0.001). The risk of an ECG abnormality was about three times higher in SM than healthy children (p<0.001; OR=2.89;95%CI[1.68,4.99). Conclusion: Severe malaria patients had significant ECG abnormalities (Sinus Tachycardia). |
| Databáze: | MEDLINE |
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